Latifi Masoomeh, Rahim Forough, Ahmadlou Mojtaba, Pouladian Nima, Allahbakhshian Leili
Research and Technology, Ministry of Health and Medical Education, Tehran, Iran.
Department of Information Management, Regional Information Center for Science and Technology, Shiraz, Iran.
Adv Biomed Res. 2024 Nov 30;13:115. doi: 10.4103/abr.abr_45_24. eCollection 2024.
In the current century, air pollution is known as one of the most critical environmental problems and it is important to find the relations of air pollution and human health. Various air pollutants, such as volatile organic compounds (VOCs), can negatively affect women's fertility. An exhaustive electronic search was done from 2013 until July 2023 in PUBMED and The Cochrane Central Register of Controlled Trials. The following keywords were combined using Boolean hints in the databases queried: air pollution AND (fertility OR miscarriage OR embryo quality OR embryo development OR pregnancy OR implantation OR live birth). The randomized controlled trials, case-control and cohort studies analyzing the impact of air pollutants on fertility were included in the review. In this systematic review, a significant relation was found between the increase in air pollution and the reduction of fertility health, live birth rates, embryo quality, fertility, implantation rates, and miscarriage in exposed women. These results suggest low fertility health rates are associated with traffic-related air pollution. This review has concluded four components (particulate matter, nitrogen dioxide, sulfur, and carbon monoxide) of traffic pollution that can impair women's fertility. Air pollution harms women's fertility. These effects affect gamete's quality at the genetic and epigenetic level. These effects also alter fetal development. Studies have also reported an effect on fetal growth with increased miscarriages. Since air pollution is everywhere and has many sources, it seems necessary to increase the awareness of people and government officials, especially in hygiene and health, to limit air pollutants as much as possible.
在本世纪，空气污染被认为是最严重的环境问题之一，找出空气污染与人类健康之间的关系很重要。各种空气污染物，如挥发性有机化合物（VOCs），会对女性生育能力产生负面影响。从2013年到2023年7月，我们在PubMed和Cochrane对照试验中央注册库进行了详尽的电子检索。在查询的数据库中，使用布尔逻辑运算符组合了以下关键词：空气污染AND（生育能力OR流产OR胚胎质量OR胚胎发育OR怀孕OR着床OR活产）。纳入综述的是分析空气污染物对生育能力影响的随机对照试验、病例对照研究和队列研究。在这项系统综述中，发现空气污染增加与受暴露女性的生育健康、活产率、胚胎质量、生育能力、着床率和流产率降低之间存在显著关联。这些结果表明，低生育健康率与交通相关的空气污染有关。该综述总结出交通污染的四个组成部分（颗粒物、二氧化氮、硫和一氧化碳）会损害女性的生育能力。空气污染会损害女性的生育能力。这些影响在基因和表观遗传水平上影响配子质量。这些影响还会改变胎儿发育。研究还报告了空气污染增加导致流产，对胎儿生长也有影响。由于空气污染无处不在且来源众多，似乎有必要提高人们和政府官员的意识，尤其是在卫生和健康方面，尽可能限制空气污染物。
