带有苄胺的高价碘（III）试剂与亚磺酸盐的反应活性。

Dedeiras Beatriz, Caldeira Catarina S, Cunha José C, Gomes Clara S B, Marques M Manuel B

LAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, NOVA FCT , 2829-516 Caparica, Portugal.

Beilstein J Org Chem. 2024 Dec 19;20:3281-3289. doi: 10.3762/bjoc.20.272. eCollection 2024.

The reactivity of our recently disclosed hypervalent iodine reagents (HIRs) bearing a benzylamine with in situ-generated sulfenate salts was investigated. Under the studied conditions sulfonamides have been obtained in up to 52% yield. This reaction has been extended to a variety of HIRs and sulfenate salts to explore the different reactivity of these new reagents. A plausible mechanism is proposed, suggesting a possible radical pathway.

我们研究了最近公开的带有苄胺的高价碘试剂（HIRs）与原位生成的亚磺酸盐的反应活性。在所研究的条件下，已获得了产率高达52%的磺酰胺。该反应已扩展到多种HIRs和亚磺酸盐，以探索这些新试剂的不同反应活性。提出了一个合理的机理，表明可能存在自由基途径。