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完全性葡萄胎与并存正常胎儿双胎妊娠的成功保守治疗:一例报告

A Successful Conservative Management of Twin Gestation of Complete Molar Gestation and Co-Existing Normal Fetus: A Case Report.

作者信息

Ahmad Sadaf, G R Dhivyambigai, Subramanyan Annapurneswari, Amalraj Sindhuja, M Elamathi

机构信息

Histopathology, Apollo Cancer Centre, Chennai, IND.

Obstetrics and Gynaecology, Apollo Cradle Hospitals, Chennai, IND.

出版信息

Cureus. 2024 Nov 22;16(11):e74275. doi: 10.7759/cureus.74275. eCollection 2024 Nov.

Abstract

Twin pregnancies consisting of one normal fetus and one complete mole are very rare. The main concerning risks associated with the continuation of such pregnancy are hyperthyroidism, theca lutein cysts, preeclampsia, and the development of GTD (gestational trophoblastic disease) spectrum (neoplasia) in the mother, which is due to high human chorionic gonadotropin (HCG) values, and intrauterine death and prematurity in the coexistent normal fetus. We report the successful outcome of conservative management in a healthy mother and baby. A 29-year-old patient was diagnosed with a complete mole and coexisting fetus in the 13th week of pregnancy. The risks of continuing with molar pregnancy were discussed in detail with the patient after informed consent to continue the pregnancy was obtained. With close monitoring, the pregnancy progressed, and she had spontaneous preterm labor and delivered an alive, healthy baby at 34 weeks. Post-delivery, the mother and child had no complications. Follow-up beta HCG dropped to less than 5 IU/mL at six weeks post-delivery. However, close follow-up was continued for the next six months, ensuring optimum health for the mother.

摘要

由一个正常胎儿和一个完全性葡萄胎组成的双胎妊娠非常罕见。继续此类妊娠主要涉及的风险包括甲状腺功能亢进、黄素囊肿、子痫前期以及母亲发生妊娠滋养细胞疾病(GTD)谱系(肿瘤形成),这是由于人绒毛膜促性腺激素(HCG)值升高所致,同时还包括并存的正常胎儿发生宫内死亡和早产。我们报告了一例健康母婴保守治疗成功的病例。一名29岁患者在妊娠第13周被诊断为完全性葡萄胎合并胎儿。在获得患者继续妊娠的知情同意后,详细讨论了继续妊娠的风险。经过密切监测,妊娠得以继续,患者出现自发性早产,并在34周时分娩出一个存活的健康婴儿。产后,母婴均无并发症。产后六周随访时,β-HCG降至5 IU/mL以下。然而,在接下来的六个月继续密切随访,确保母亲的最佳健康状态。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9125/11664112/e4b08e0a0454/cureus-0016-00000074275-i01.jpg

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