Hosseini Mahdieh, Kassavetis Panagiotis, Hallett Mark
National Institute of Neurological Disorders and Stroke (NINDS), Human Motor Control Section, National Institutes of Health, Bethesda, MD, United States.
Adult Neurology Residency Program, University of California, Los Angeles, Los Angeles, CA, United States.
Dystonia. 2023;2. doi: 10.3389/dyst.2023.11385. Epub 2023 Jun 15.
Blepharospasm (BSP) is a focal dystonia. There is a lack of standardization in the length of time necessary to get a measure of BSP severity for rating scales.
Thirty-eight, 2-min-long standardized videos of subjects with BSP without any other dystonias were reviewed (group1). Eye closure rate was measured in 0-60 s vs. 60-120 s. Wilcoxon signed-rank test and Spearman correlation coefficient were used to compare the eye closure rate between these two intervals. An additional 68 standardized videos of subjects with blepharospasm associated with dystonia of the head were reviewed (group2). Presence, phenomenology and concordance between what subjects verbally reported as their sensory trick and what they demonstrated was classified for both groups then qualitatively compared.
RESULTS/CONCLUSION: Eye closure rates between 0-60 s and 0-120 s were not statistically different. There is no added benefit of counting the number of eye closures in 2 min, compared to 1 min, in patients with BSP. Sensory trick was reported by 57% of subjects with BSP and 80% of subjects who have blepharospasm and other dystonias of the head. With 100% and 97% concordance, patients' self-reported sensory trick accurately describes the movements that alleviate their dystonic movements.
睑痉挛（BSP）是一种局限性肌张力障碍。在使用评定量表测量BSP严重程度所需的时间长度方面缺乏标准化。
1）确定评估睑痉挛患者在1分钟与2分钟内的闭眼次数之间的差异。2）描述仅患有睑痉挛的受试者与患有与头部其他肌张力障碍相关的睑痉挛的受试者中感觉技巧的患病率、现象学和一致性。
回顾了38段时长为2分钟的无任何其他肌张力障碍的BSP受试者的标准化视频（第1组）。在0 - 60秒与60 - 120秒测量闭眼率。使用Wilcoxon符号秩检验和Spearman相关系数来比较这两个时间段之间的闭眼率。另外回顾了68段患有与头部肌张力障碍相关的睑痉挛的受试者的标准化视频（第2组）。对两组受试者口头报告的感觉技巧与其所展示的内容之间的存在情况、现象学和一致性进行分类，然后进行定性比较。
结果/结论：0 - 60秒与0 - 120秒之间的闭眼率无统计学差异。对于BSP患者，与1分钟相比，在2分钟内计算闭眼次数并无额外益处。57%的BSP受试者和80%患有睑痉挛及头部其他肌张力障碍的受试者报告有感觉技巧。患者自我报告的感觉技巧与缓解其肌张力障碍性运动的动作的一致性分别为100%和97%，能准确描述这些动作。
