Gómez-Wong E, Martí M J, Cossu G, Fabregat N, Tolosa E S, Valls-Solé J
Unitat d'EMG, Department de Medicina, IDIBAPS, Hospital Clínic, Universitat de Barcelona, Spain.
Neurosci Lett. 1998 Jul 24;251(2):125-8. doi: 10.1016/s0304-3940(98)00519-9.
The mechanism of action of the 'geste antagonistique', or sensory trick, used by patients with dystonic blepharospasm (BSP) to transiently diminish their symptoms is presently unknown. In this paper we examined the effects induced by a sensory trick consisting of finger contact with the face on the electrically induced blink reflex and the blink reflex excitability recovery curve to paired stimuli. The results were compared with those obtained in a group of six healthy volunteers who mimicked the manoeuvre used by the patients as a sensory trick. In all subjects, the area of R2 was significantly reduced, and the amplitude of R1 was significantly enhanced, during a mean of 10 min after the onset of finger-face contact in comparison to rest. However, there were no changes in the blink reflex excitability recovery curve. The contact-induced effect on the magnitude of the R2 component of the blink reflex is probably caused by sensory gating on trigeminal afferents. Such a reduction in the gain of trigemino-facial reflexes may partly underly the transient benefit experienced by patients with BSP with the use of sensory tricks.
张力障碍性眼睑痉挛（BSP）患者用来短暂减轻症状的“拮抗动作”或感觉技巧的作用机制目前尚不清楚。在本文中，我们研究了手指接触面部这种感觉技巧对电诱发眨眼反射以及对成对刺激的眨眼反射兴奋性恢复曲线的影响。将结果与一组六名健康志愿者的结果进行比较，这些志愿者模仿患者作为感觉技巧所使用的动作。在所有受试者中，与休息时相比，手指与面部接触开始后的平均10分钟内，R2的面积显著减小，R1的幅度显著增强。然而，眨眼反射兴奋性恢复曲线没有变化。接触对面部眨眼反射R2成分大小的影响可能是由三叉神经传入纤维的感觉门控引起的。三叉神经-面部反射增益的这种降低可能部分是BSP患者使用感觉技巧时所体验到的短暂益处的基础。
