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鉴别大疱性固定型药疹与史蒂文斯-约翰逊综合征的临床线索:病例报告

Clinical cues for distinguishing bullous fixed drug eruption from Stevens-Johnson syndrome: A case report.

作者信息

Samman Luna, Fernandez Chloe, Dukharan Victoria, Dominguez Patrick

机构信息

Garnet Health Medical Center, Middletown, NY, USA.

Department of Dermatology, KCU-GME Consortium/Advanced Dermatology and Cosmetic Surgery, Orlando, FL, USA.

出版信息

SAGE Open Med Case Rep. 2024 Dec 23;12:2050313X241307117. doi: 10.1177/2050313X241307117. eCollection 2024.

Abstract

This case report discusses two clinical encounters of a 62-year-old Hispanic woman initially hospitalized with suspected Stevens-Johnson syndrome, later correctly diagnosed with bullous fixed drug eruption during an outpatient visit for a similar eruption. The first encounter involved an extensive evaluation and an 11-day hospital stay, while the second was managed successfully as an outpatient with oral prednisone. This report highlights the importance of differentiating bullous fixed drug eruption from Stevens-Johnson syndrome/toxic epidermal necrolysis and emphasizes the need for a collaborative approach between Primary Care Providers and Dermatology to ensure optimal patient care.

摘要

本病例报告讨论了一名62岁西班牙裔女性的两次临床就诊情况。该患者最初因疑似史蒂文斯-约翰逊综合征住院,后来在门诊就诊时因类似皮疹被正确诊断为大疱性固定性药疹。第一次就诊涉及全面评估和11天的住院治疗,第二次则作为门诊患者成功使用口服泼尼松进行治疗。本报告强调了区分大疱性固定性药疹与史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症的重要性,并强调了初级保健提供者和皮肤科之间采取协作方法以确保为患者提供最佳护理的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4932/11664546/34a1d7b649ab/10.1177_2050313X241307117-fig1.jpg

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