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仿生纳米载体:整合天然功能以实现高级治疗应用

Biomimetic nanocarriers: integrating natural functions for advanced therapeutic applications.

作者信息

Perini Hugo Felix, Matos Beatriz Sodré, de Oliveira Carlo José Freire, da Silva Marcos Vinicius

机构信息

Department of Immunology, Microbiology and Parasitology. Biological and Natural Sciences Institute. Federal University of Triângulo Mineiro. Uberaba, Minas Gerais, Brazil.

出版信息

Beilstein J Nanotechnol. 2024 Dec 16;15:1619-1626. doi: 10.3762/bjnano.15.127. eCollection 2024.

Abstract

Biomimetic nanocarriers, engineered to mimic the characteristics of native cells, offer a revolutionary approach in the treatment of various complex human diseases. This strategy enhances drug delivery by leveraging the innate properties of cellular components, thereby improving biocompatibility and targeting specificity. Biomimetic nanocarriers demonstrate significant advancements in drug delivery systems against cancer therapy, Alzheimer's disease, autoimmune diseases, and viral infections such as COVID-19. Here, we address the therapeutic applications of biomimetic nanocarriers and their promising strategy for personalized medicine.

摘要

仿生纳米载体经过设计以模仿天然细胞的特征,为治疗各种复杂的人类疾病提供了一种革命性的方法。这种策略通过利用细胞成分的固有特性来增强药物递送,从而提高生物相容性和靶向特异性。仿生纳米载体在针对癌症治疗、阿尔茨海默病、自身免疫性疾病以及COVID-19等病毒感染的药物递送系统中展现出显著进展。在此,我们阐述了仿生纳米载体的治疗应用及其在个性化医学方面的前景策略。

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