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黏膜直肠切除术和回肠造口术作为传统直肠切除术的替代方案。

Mucosal proctectomy and ileostomy as an alternative to conventional proctectomy.

作者信息

Fasth S, Oresland T, Ahrén C, Hultén L

出版信息

Dis Colon Rectum. 1985 Jan;28(1):31-4. doi: 10.1007/BF02553903.

Abstract

Endoanal mucosal proctectomy with preservation of the anal sphincters has been employed as an alternative to the traditional method of rectal excision in 23 patients with ulcerative colitis or Crohn's disease. Ten patients in whom the anal canal was left open and drained had uneventful postoperative courses. Of the remaining 13 patients in whom the top of the anal remnant was oversewn, four had local pelvic sepsis that resolved in a few weeks' time and one patient had a pelvic hematoma requiring relaparotomy and sphincter muscle excision. Postoperative disturbances in bladder or sexual function did not occur in any of the patients. At the latest follow-up (mean 21 months), all patients were fully satisfied with the result of the operation. On proctoscopic examination, an anal remnant, measuring approximately 3 cm from the anal verge, could be demonstrated. Its upper end had healed with a fibrous scar in 50 percent of the patients, whereas a small area of friable granulation tissue, sometimes with a short sinus tract was still observed in the others. The persistence of such lesions was associated with minor mucous discharge occasionally escaping from the anal canal. Biopsies disclosed regeneration of cylindric and transitional types of epithelium. The fate of these epithelial remnants remains to be seen. Endoanal mucosal proctectomy appears to be an attractive alternative to the conventional technique. It prevents a great deal of morbidity and enhances postoperative rehabilitation.

摘要

对23例溃疡性结肠炎或克罗恩病患者采用保留肛门括约肌的经肛门黏膜直肠切除术,作为传统直肠切除方法的替代方案。10例肛管开放引流的患者术后恢复顺利。其余13例肛门残端顶部缝合的患者中,4例发生局部盆腔感染,数周后好转,1例患者发生盆腔血肿,需要再次剖腹手术并切除括约肌。所有患者均未出现膀胱或性功能术后障碍。在最近一次随访(平均21个月)时,所有患者对手术结果均非常满意。直肠镜检查显示,距肛缘约3 cm处可见肛门残端。50%的患者其上端已愈合形成纤维瘢痕,而其他患者仍可见一小片易碎的肉芽组织,有时伴有短窦道。这些病变的持续存在与偶尔从肛管流出少量黏液有关。活检显示有柱状上皮和移行上皮再生。这些上皮残余物的转归有待观察。经肛门黏膜直肠切除术似乎是一种有吸引力的传统技术替代方案。它可避免大量并发症并促进术后康复。

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