Debnath Pradipta, Tkach Jean A, Abramson Zachary R, Abu Ata Nadeen K, Coley Brian D, Epstein Katherine N, Griffin Lindsay, Zhang Bin, Trout Andrew T, Dillman Jonathan, Morin Cara E
Cincinnati Children's Hospital Medical Center, Cincinnati, USA.
University of Cincinnati, Cincinnati, USA.
Abdom Radiol (NY). 2024 Dec 24. doi: 10.1007/s00261-024-04765-z.
Implementation of diffusion-weighted imaging (DWI) for abdominal imaging in children has challenges due to motion artifacts exacerbated by long acquisition times. We aimed to compare acquisition time and image quality between conventional DWI and multi-band (MB) DWI of the liver in children and young adults.
Clinical MRI exams from May 2023 to January 2024 were reviewed, including four DWI sequences: respiratory-triggered (RTr, clinical standard), free-breathing (FB), MB-DWI with shift factor 1 (MBsf1), and MB-DWI with shift factor 2 (MBsf2). Acquisition times were recorded, and signal intensity and apparent signal-to-noise ratio (aSNR) were calculated for the liver and spleen. Six blinded pediatric radiologists independently assessed image quality, artifacts, and lesion visualization on a 5-point Likert scale and identified their preferred sequence. Statistical comparisons were made using Kruskal-Wallis and ANOVA tests.
Median acquisition times were significantly reduced with MB-DWI (43 s for MBsf1/MBsf2) compared to FB (84 s) and RTr (240 s). Image quality and artifact scores were highest for RTr and FB sequences (p < 0.0001). Mean image quality scores were 3.7 (RTr, FB), 3.4 (MBsf1), and 3.5 (MBsf2), while artifact scores followed a similar trend (higher score = fewer artifacts). Lesion visualization scores were comparable across sequences (p = 0.11), and reviewers expressed no preference in 47% of cases. Apparent diffusion coefficient (ADC) values were consistent across all sequences (p > 0.05).
MB-DWI significantly reduces acquisition time while maintaining acceptable image quality and lesion visualization, making it a valuable option for pediatric abdominal MRI.
由于长时间采集时间加剧了运动伪影，儿童腹部成像中实施扩散加权成像（DWI）存在挑战。我们旨在比较儿童和年轻成人肝脏的传统DWI与多频段（MB）DWI之间的采集时间和图像质量。
回顾了2023年5月至2024年1月的临床MRI检查，包括四种DWI序列：呼吸触发（RTr，临床标准）、自由呼吸（FB）、移位因子为1的MB-DWI（MBsf1）和移位因子为2的MB-DWI（MBsf2）。记录采集时间，并计算肝脏和脾脏的信号强度和表观信噪比（aSNR）。六位盲法儿科放射科医生在5分李克特量表上独立评估图像质量、伪影和病变可视化情况，并确定他们偏好的序列。使用Kruskal-Wallis和方差分析进行统计比较。
与FB（84秒）和RTr（240秒）相比，MB-DWI（MBsf1/MBsf2为43秒）的中位采集时间显著缩短。RTr和FB序列的图像质量和伪影评分最高（p < 0.0001）。平均图像质量评分分别为3.7（RTr，FB）、3.4（MBsf1）和3.5（MBsf2），而伪影评分遵循类似趋势（评分越高 = 伪影越少）。各序列间病变可视化评分相当（p = 0.11），47%的病例中审阅者未表达偏好。所有序列的表观扩散系数（ADC）值一致（p > 0.05）。
MB-DWI显著缩短采集时间，同时保持可接受的图像质量和病变可视化，使其成为儿童腹部MRI的一个有价值的选择。
