Kemp Justine M, Ghosh Adarsh, Dillman Jonathan R, Krishnasarma Rekha, Manhard Mary Kate, Tipirneni-Sajja Aaryani, Shrestha Utsav, Trout Andrew T, Morin Cara E
Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.
Department of Radiology, University of Cincinnati College of Medicine, 3188 Bellevue Avenue, Cincinnati, OH, 45219, USA.
Pediatr Radiol. 2025 Jan;55(1):36-57. doi: 10.1007/s00247-024-06133-x. Epub 2025 Jan 6.
Quantitative abdominal magnetic resonance imaging (MRI) offers non-invasive, objective assessment of diseases in the liver, pancreas, and other organs and is increasingly being used in the pediatric population. Certain quantitative MRI techniques, such as liver proton density fat fraction (PDFF), R2* mapping, and MR elastography, are already in wide clinical use. Other techniques, such as liver T1 mapping and pancreas quantitative imaging methods, are emerging and show promise for enhancing diagnostic sensitivity and treatment monitoring. Quantitative imaging techniques have historically required a breath-hold, making them more difficult to implement in the pediatric population. However, technological advances, including free-breathing techniques and compressed sensing imaging, are making these techniques easier to implement. The purpose of this article is to review current liver and pancreas quantitative techniques and to provide a practical guide for implementing these techniques in pediatric practice. Future directions of liver and pancreas quantitative imaging will be briefly discussed.
定量腹部磁共振成像（MRI）能够对肝脏、胰腺及其他器官的疾病进行无创、客观的评估，并且在儿科人群中的应用越来越广泛。某些定量MRI技术，如肝脏质子密度脂肪分数（PDFF）、R2*图谱和磁共振弹性成像，已在临床中广泛应用。其他技术，如肝脏T1图谱和胰腺定量成像方法，正在兴起，并显示出提高诊断敏感性和治疗监测的前景。从历史上看，定量成像技术需要屏气，这使得它们在儿科人群中更难实施。然而，包括自由呼吸技术和压缩感知成像在内的技术进步，正在使这些技术更易于实施。本文的目的是回顾当前肝脏和胰腺的定量技术，并为在儿科实践中实施这些技术提供实用指南。还将简要讨论肝脏和胰腺定量成像的未来发展方向。
