Department of Radiology, Daxing Teaching Hospital, Capital Medical University, Beijing, 102600, China.
Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Curr Med Imaging. 2024;20(1):e15734056308153. doi: 10.2174/0115734056308153240817160848.
Magnetic Resonance Imaging (MRI) data acquisition includes several sequences that might be optimized to reduce the scan time.
This study aimed to investigate the impact of gadolinium chelate administration timing on scan duration and image quality in Diffusion-weighted Imaging (DWI) and T2-weighted Imaging (T2WI) during abdominal MRI examinations.
A prospective study was conducted from October 2018 to May 2020. Study participants were assigned into a conventional group, undergoing MRI with DWI and T2WI sequences pre and post-gadolinium injection, or an optimized group, receiving MRI with DWI and T2WI sequences after gadolinium injection. Quantitative image quality, measured by the Signal-to-noise Ratio (SNR), Contrast-to-noise Ratio (CNR), and Apparent Diffusion Coefficient (ADC), was analyzed. Kappa statistics were employed for the inter-observer agreement on liver lesion detection.
Our study has included 341 patients, with 168 and 173 in the conventional and optimized groups, respectively. Mean scan durations were 1,304 (±143) and 1,015 (±129) s for the conventional and optimized groups, respectively (p<0.05). For the liver, spleen, and pancreas, SNR and ADC remained statistically unchanged in post-enhanced DWI and T2WI (p>0.05). Significant decreases in the SNR and ADC of the kidney were observed in post-contrast DWI and T2WI (p<0.05). Hepatic lesion detectability did not show significant differences between pre and post-contrast DWI and T2WI images (p>0.05).
DWI and T2WI sequences assessed post-gadolinium administration exhibited shortened scan time without compromising the image quality for liver, spleen, and pancreas evaluations. However, these sequences should be examined before gadolinium administration when assessing the kidneys.
磁共振成像（MRI）数据采集包括多个序列，这些序列可以进行优化以减少扫描时间。
本研究旨在探讨在腹部 MRI 检查中，钆螯合物给药时间对弥散加权成像（DWI）和 T2 加权成像（T2WI）扫描时间和图像质量的影响。
前瞻性研究于 2018 年 10 月至 2020 年 5 月进行。研究参与者被分为常规组和优化组。常规组进行 MRI 检查，DWI 和 T2WI 序列在钆螯合物注射前后进行；优化组进行 MRI 检查，DWI 和 T2WI 序列在钆螯合物注射后进行。通过信噪比（SNR）、对比噪声比（CNR）和表观扩散系数（ADC）来分析图像质量。采用 Kappa 统计分析肝病变检测的观察者间一致性。
本研究共纳入 341 例患者，常规组和优化组分别为 168 例和 173 例。常规组和优化组的平均扫描时间分别为 1304（±143）和 1015（±129）s（p<0.05）。对于肝脏、脾脏和胰腺，增强后 DWI 和 T2WI 的 SNR 和 ADC 保持统计学不变（p>0.05）。增强后 DWI 和 T2WI 的肾脏 SNR 和 ADC 显著降低（p<0.05）。肝病变在增强前后的 DWI 和 T2WI 图像上的检测能力无显著差异（p>0.05）。
在不影响肝脏、脾脏和胰腺评估的情况下，钆螯合物给药后评估的 DWI 和 T2WI 序列缩短了扫描时间。然而，在评估肾脏时，这些序列应该在钆螯合物给药前进行检查。
