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2021 - 2022年印度喀拉拉邦国家结核病消除计划(NTEP)下耐多药结核病(DR - TB)管理部分的评估

Evaluation of the Drug-Resistant Tuberculosis (DR-TB) management component under the National Tuberculosis Elimination Program (NTEP) in Kerala, India, 2021-22.

作者信息

Vaman Raman Swathy, Kalyanasundaram Madhanraj, Mohan Malu, Pradeepa Narayana, Murhekar Manoj V

机构信息

Assistant Director of Health Services, District Hospital, Kanhangad, Kasaragod, Kerala, India.

Scientist E, ICMR-National Institute of Epidemiology, Chennai, Tamil Nadu, India.

出版信息

Lung India. 2025 Jan 1;42(1):16-24. doi: 10.4103/lungindia.lungindia_355_24. Epub 2024 Dec 24.

Abstract

BACKGROUND AND OBJECTIVE

We evaluated the DR-TB component of the National Tuberculosis Elimination Program (NTEP) in a high-burden district in Kerala to identify the programmatic gaps, if any, in screening, diagnosis, treatment, and follow-up of notified DR-TB patients.

METHODS

A mixed-methods design was used, and the evaluation was performed in two steps. In the first step, we reviewed the program documents and conducted stakeholder interviews to develop a detailed description of the program design and developed a logical framework to evaluate program performance. Consequently, in the next step, we conducted programmatic data reviews, facility surveys, and in-depth interviews with key stakeholders to identify the programmatic gaps in implementation, guided by the logic framework.

RESULTS

Of the 494 microbiologically confirmed TB patients during 2021-22, 342 (69%) were tested for drug sensitivity, and 30 DR-TB patients were identified. There was no separate district DR-TB treatment center with airborne infection control facilities, and only 16% (66/422) of the various categories of staff were trained in recent guidelines. Only 30% (9/30) of DR-TB patients were provided with any psychological assessment. The favorable treatment outcome was 80% Interviews revealed poor readiness and motivation from the private sector for screening, contextual barriers in human resource availability, transportation, and financial barriers to the beneficiary despite providing financial benefits.

CONCLUSION

Prioritizing the establishment of a district DR-TB treatment center and sputum transport mechanism, posting a clinical psychologist dedicated to counseling patients on therapy, and training all categories of staff on DR-TB management guidelines will significantly contribute to improving program outcomes.

摘要

背景与目的

我们在喀拉拉邦的一个高负担地区对国家结核病消除计划(NTEP)中的耐多药结核病部分进行了评估,以确定在已通报的耐多药结核病患者的筛查、诊断、治疗及随访方面是否存在任何计划上的差距。

方法

采用混合方法设计,评估分两步进行。第一步,我们审查了计划文件并与利益相关者进行访谈,以详细描述计划设计,并制定了一个逻辑框架来评估计划执行情况。因此,在下一步中,我们在逻辑框架的指导下,进行了计划数据审查、机构调查以及与关键利益相关者的深入访谈,以确定实施过程中的计划差距。

结果

在2021 - 2022年期间确诊的494例微生物学确诊结核病患者中,342例(69%)进行了药敏试验,确诊了30例耐多药结核病患者。没有设有空气传播感染控制设施的独立地区耐多药结核病治疗中心,各类工作人员中只有16%(66/422)接受了近期指南的培训。仅30%(9/30)的耐多药结核病患者接受了任何心理评估。良好治疗结局为80%。访谈显示,私营部门在筛查方面准备不足且积极性不高,存在人力资源可及性方面的背景障碍、交通问题,以及尽管提供了经济福利,但受益人仍面临经济障碍。

结论

优先建立地区耐多药结核病治疗中心和痰液运输机制,安排一名临床心理学家专门为患者提供治疗咨询,并对各类工作人员进行耐多药结核病管理指南培训,将显著有助于改善计划成果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/11789963/c0a7a6495210/LI-42-16-g001.jpg

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