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农药与人类健康

Pesticides and human health.

作者信息

Rodrigues Marina de Barros, da Silva Carlos Augusto Mello, Chong-Silva Débora Carla, Chong-Neto Herberto José

机构信息

Departament of Pediatrics, Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brazil.

Board Certification in Medical Toxicology - Departamento Científico de Toxicologia e Saúde Ambiental da Sociedade Brasileira de Pediatria, Brazil.

出版信息

J Pediatr (Rio J). 2025 Mar-Apr;101 Suppl 1(Suppl 1):S70-S76. doi: 10.1016/j.jped.2024.11.008. Epub 2024 Dec 24.

DOI:10.1016/j.jped.2024.11.008
PMID:39719018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11962559/
Abstract

OBJECTIVES

to review scientific evidence on the impacts of pesticides on child health, addressing prenatal and postnatal exposures, acute and chronic effects.

DATA SOURCE

narrative literature review, using databases such as PubMed, SciELO and Google Scholar. The inclusion criteria involved studies published between 2000 and 2023 that analyzed the relationship between pesticides and child health, including systematic reviews, cohort studies, case-control studies and clinical trials. The descriptors used were "pesticides," "child health," "prenatal exposure," "environmental health," and "developmental toxicity."

DATA SYNTHESIS

In this review, an association was observed between exposure to pesticides and the development of neurological and endocrinological diseases, childhood cancer and immunological diseases.

CONCLUSIONS

Pesticides represent a significant risk to children's health, with impacts ranging from neurological alterations to chronic diseases. It is essential to promote regulatory changes and encourage agricultural practices that are less dependent on chemical substances, in addition to investing in research that explores long-term impacts and mitigation strategies.

摘要

目的

回顾关于农药对儿童健康影响的科学证据,涉及产前和产后暴露、急性和慢性影响。

数据来源

采用叙述性文献综述,使用如PubMed、SciELO和谷歌学术等数据库。纳入标准包括2000年至2023年间发表的分析农药与儿童健康关系的研究,包括系统评价、队列研究、病例对照研究和临床试验。使用的描述词为“农药”“儿童健康”“产前暴露”“环境卫生”和“发育毒性”。

数据综合

在本次综述中,观察到接触农药与神经和内分泌疾病、儿童癌症及免疫疾病的发生之间存在关联。

结论

农药对儿童健康构成重大风险,影响范围从神经改变到慢性疾病。除了投资探索长期影响和缓解策略的研究外,促进监管变革并鼓励减少对化学物质依赖的农业实践至关重要。

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Gestational organophosphate pesticide exposure and childhood cardiovascular outcomes.妊娠期间接触有机磷农药与儿童心血管结局。
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Characterization of pesticide exposures and their associations with asthma morbidity in a predominantly low-income urban pediatric cohort in Baltimore City.巴尔的摩市以低收入为主的城市儿科队列中,农药暴露及其与哮喘发病率的关系特征。
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Exposure to agricultural pesticides and wheezing among 5-12-year-old children in the Imperial Valley, CA, USA.美国加利福尼亚州帝王谷5至12岁儿童接触农用杀虫剂与气喘的情况。
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Organophosphate insecticide exposure and respiratory symptoms among school children in Northern Thailand: Interaction by biomass burning, dampness and season.有机磷杀虫剂暴露与泰国北部学童呼吸道症状:生物质燃烧、潮湿和季节的交互作用。
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Association of pyrethroids exposure with asthma in US children and adolescents: a nationally representative cross-sectional study.美国儿童和青少年中拟除虫菊酯暴露与哮喘的关系:一项具有全国代表性的横断面研究。
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Environmental Exposure to Pesticides and the Risk of Child Neurodevelopmental Disorders.环境暴露于农药与儿童神经发育障碍风险。
Medicina (Kaunas). 2024 Mar 13;60(3):475. doi: 10.3390/medicina60030475.
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