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肺无症状复发性空洞性结节病:一例报告。

Pulmonary asymptomatic recurrent cavitary sarcoidosis: A case report.

作者信息

Pak Alexey, Baigenzhin Abai, Zarkumova Zhanar, Chuvakova Elmira, Peradze Manana, Zaripova Lina

机构信息

JSC National Scientific Medical Center, 42 Abylai Khan ave., 010009, Astana, Kazakhstan.

NCJSC Astana Medical University, 49/A Beibitshilik st., 010000, Astana, Kazakhstan.

出版信息

Heliyon. 2024 Dec 6;10(24):e41041. doi: 10.1016/j.heliyon.2024.e41041. eCollection 2024 Dec 30.

DOI:10.1016/j.heliyon.2024.e41041
PMID:39720041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11667682/
Abstract

Cavitary sarcoidosis is a rare form and represents non-caseating granulomatous diseases of the lungs exhibiting a narrow range of differential diagnoses. The peculiarity of this case lies in the difficulty of distinguishing atypical manifestations of pulmonary sarcoidosis, such as cystic lesions, from cavernous tuberculosis. Both possess similar clinical and radiological features. We report a case of a 36-year-old male, who has been under observation since 2019 without active complaints. Chest computed tomography revealed bilateral reticulo-nodular changes with the formation of extensive consolidation areas and cavities, аs well as mediastinal lymphadenopathy. This article represents clinical case of patient with recurrent cavitary sarcoidosis and underscores the necessity for monitoring and adjusting of the treatment of this complex condition because their course may be punctuated by several complications including pleural effusion, hemoptysis, aspergilloma, and pneumothorax.

摘要

空洞型结节病是一种罕见的类型,代表肺部的非干酪样肉芽肿性疾病,鉴别诊断范围较窄。该病例的特殊性在于难以将肺部结节病的非典型表现(如囊性病变)与空洞型肺结核区分开来。两者具有相似的临床和放射学特征。我们报告一例36岁男性病例,自2019年以来一直在观察中,无活动性主诉。胸部计算机断层扫描显示双侧网状结节改变,伴有广泛实变区和空洞形成,以及纵隔淋巴结肿大。本文介绍了一例复发性空洞型结节病患者的临床病例,并强调了监测和调整这种复杂疾病治疗的必要性,因为其病程可能会出现包括胸腔积液、咯血、曲菌球和气胸在内的多种并发症。

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Pulmonary asymptomatic recurrent cavitary sarcoidosis: A case report.肺无症状复发性空洞性结节病:一例报告。
Heliyon. 2024 Dec 6;10(24):e41041. doi: 10.1016/j.heliyon.2024.e41041. eCollection 2024 Dec 30.
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[A case of sarcoidosis with right pneumothorax and multiple cavities in both lung fields].[1例结节病合并右侧气胸及双肺多发空洞]
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本文引用的文献

1
Infectious Complications of Pulmonary Sarcoidosis.肺结节病的感染性并发症
J Clin Med. 2024 Jan 7;13(2):342. doi: 10.3390/jcm13020342.
2
Sarcoidosis: Updates on therapeutic drug trials and novel treatment approaches.结节病:治疗药物试验及新治疗方法的最新进展
Front Med (Lausanne). 2022 Oct 12;9:991783. doi: 10.3389/fmed.2022.991783. eCollection 2022.
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ERS clinical practice guidelines on treatment of sarcoidosis.ERS 临床实践指南:结节病的治疗。
Eur Respir J. 2021 Dec 16;58(6). doi: 10.1183/13993003.04079-2020. Print 2021 Dec.
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Pulmonary sarcoidosis: from clinical features to pathology- narrative review.肺结节病:从临床特征到病理-叙述性综述。
Ann Palliat Med. 2021 Mar;10(3):3438-3444. doi: 10.21037/apm-21-344.
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Sarcoidosis: A Clinical Overview from Symptoms to Diagnosis.结节病:从症状到诊断的临床概述。
Cells. 2021 Mar 31;10(4):766. doi: 10.3390/cells10040766.
6
The incidence, comorbidity and mortality of sarcoidosis in Korea, 2008-2015: a nationwide population-based study.2008 - 2015年韩国结节病的发病率、合并症及死亡率:一项基于全国人口的研究
Sarcoidosis Vasc Diffuse Lung Dis. 2020;37(1):24-26. doi: 10.36141/svdld.v37i1.7660. Epub 2020 Mar 15.
7
Outcome of pulmonary sarcoidosis: a population-based study 1976-2013.肺结节病的转归:一项基于人群的1976 - 2013年研究。
Sarcoidosis Vasc Diffuse Lung Dis. 2018;35(2):123-128. doi: 10.36141/svdld.v35i2.6356. Epub 2018 Apr 28.
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Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline.结节病的诊断与检测:美国胸科学会临床实践指南
Am J Respir Crit Care Med. 2020 Apr 15;201(8):e26-e51. doi: 10.1164/rccm.202002-0251ST.
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Primary cavitary sarcoidosis: A case report, systematic review, and proposal of new diagnostic criteria.原发性空洞型结节病:一例病例报告、系统评价及新诊断标准的提议
Lung India. 2018 Jan-Feb;35(1):41-46. doi: 10.4103/lungindia.lungindia_225_17.
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Multidisciplinary approach and long-term follow-up in a series of 640 consecutive patients with sarcoidosis: Cohort study of a 40-year clinical experience at a tertiary referral center in Barcelona, Spain.对640例连续性结节病患者采用多学科方法及长期随访:西班牙巴塞罗那一家三级转诊中心40年临床经验的队列研究
Medicine (Baltimore). 2017 Jul;96(29):e7595. doi: 10.1097/MD.0000000000007595.