Zhu Tingting, Ge Yiping, Zhang Jiechen, Chen Yan, Zhong Huajie, Yang Li, Zhang Juan, Li Ke, Yang Shuyun
Department of Dermatology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.
Department of Cosmetic Laser Surgery, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, People's Republic of China.
Clin Cosmet Investig Dermatol. 2024 Dec 20;17:3013-3021. doi: 10.2147/CCID.S484957. eCollection 2024.
Acne is a common inflammatory dermatosis. Although gender-related differences in prevalence and age of onset have been documented. Other gender-related characteristics of acne have not been well elucidated yet.
We compared characteristics of skin lesions, severity and risk factors of acne between males and females in Chinese.
Investigator-administered questionnaire was used to collect demographic data, clinical feature and risk factors of acne from May 2020 to August 2021. All participants were from outpatient clinics in seven cities, China.
A total of 13085 participants, including 4746 males (36.27%) and 8339 females (63.73%), aged 8 to 35 years old, completed the questionnaire. The age of onset of acne was significantly younger in males than in females(p<0.001). More females than males had comedones(83.76% vs 75.22%, p<0.001). In contrast, more males than females had pustules, cyst/nodules, scars and severer lesions(p<0.001). Moreover, the major risk factors for acne were constipation, cosmetics, dairy and sweet foods for females, while the major risk factors for males were computer usage/playing electronic games, staying up late at night, intake of hot or spicy foods. More females than males experienced good response to photodynamic treatment(79.52% vs 52.86%, p<0.05).
Acne appears earlier in males than in females. Clinical features and risk factors for acne differ between males and females. More females than males experience good response to photodynamic therapy.
This questionnaire survey was carried out in Chinese aged 8 to 35 years old. Gender-related characteristics in other ages and regions remain to be explored.
痤疮是一种常见的炎症性皮肤病。尽管已记录了痤疮患病率和发病年龄的性别差异，但痤疮的其他性别相关特征尚未得到充分阐明。
我们比较了中国男性和女性痤疮的皮肤损害特征、严重程度及危险因素。
采用研究者自行管理的问卷，于2020年5月至2021年8月收集痤疮的人口统计学数据、临床特征和危险因素。所有参与者均来自中国七个城市的门诊。
共有13085名年龄在8至35岁的参与者完成了问卷，其中男性4746名（36.27%），女性8339名（63.73%）。男性痤疮的发病年龄显著低于女性（p<0.001）。女性粉刺患者多于男性（83.76%对75.22%，p<0.001）。相比之下，男性脓疱、囊肿/结节、瘢痕及更严重皮损的患者多于女性（p<0.001）。此外，女性痤疮的主要危险因素是便秘、化妆品、乳制品和甜食，而男性的主要危险因素是使用电脑/玩电子游戏、熬夜、食用辛辣食物。女性对光动力治疗的反应优于男性（79.52%对52.86%，p<0.05）。
男性痤疮发病早于女性。男性和女性痤疮的临床特征及危险因素存在差异。女性对光动力治疗的反应优于男性。
本问卷调查针对的是8至35岁的中国人。其他年龄和地区的性别相关特征仍有待探索。
