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妊娠期新发失神性癫痫持续状态:一例报告

New Onset Absence Status Epilepticus in Pregnancy: A Case Report.

作者信息

Mutlu Onur Anil, Türk Bengi Gül, Asan Furkan

机构信息

Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.

出版信息

J Epilepsy Res. 2024 Dec 10;14(2):94-96. doi: 10.14581/jer.24015. eCollection 2024 Dec.

DOI:10.14581/jer.24015
PMID:39720199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11664049/
Abstract

Absence status epilepticus may occur in persons diagnosed with idiopathic/genetic epilepsy as well as in adult and elderly patients. Despite being a rare phenomenon, pregnant women with no previous history of epileptic seizures may be presented with new onset status epilepticus. In this report, we describe the case of a 22-year-old pregnant female with no prior history of seizures. The patient was admitted to our center with reduced spontaneous speech and perplexity. Electroencephalography showed continuous, generalized synchronous paroxysms of 3 Hz spike-wave complexes. The patient's clinical condition improved following the administration of diazepam and levetiracetam. To the best of our knowledge, we describe the first case of new onset absence status epilepticus during pregnancy.

摘要

失神癫痫持续状态可能发生在被诊断为特发性/遗传性癫痫的患者以及成人和老年患者中。尽管这是一种罕见现象,但既往无癫痫发作史的孕妇也可能出现新发癫痫持续状态。在本报告中,我们描述了一名22岁无癫痫发作史的怀孕女性的病例。该患者因自发言语减少和困惑而入住我们中心。脑电图显示3Hz棘慢复合波的持续、广泛性同步阵发性放电。给予地西泮和左乙拉西坦后患者的临床状况有所改善。据我们所知,我们描述了首例孕期新发失神癫痫持续状态的病例。

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本文引用的文献

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Status epilepticus in pregnancy.妊娠期癫痫持续状态
Epilepsy Behav. 2023 Jan;138:109034. doi: 10.1016/j.yebeh.2022.109034. Epub 2022 Dec 14.
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ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions.ILAE 特发性全面性癫痫综合征定义:ILAE 分类和定义委员会专题工作组的立场声明。
Epilepsia. 2022 Jun;63(6):1475-1499. doi: 10.1111/epi.17236. Epub 2022 May 3.
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New-onset epilepsy in women with first time seizures during pregnancy.妊娠期首次发作痫性发作的女性中新发癫痫。
Seizure. 2020 Aug;80:42-45. doi: 10.1016/j.seizure.2020.05.022. Epub 2020 Jun 2.
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Clinical characteristics and pregnancy outcomes of new onset epilepsy during pregnancy.妊娠期新发癫痫的临床特征与妊娠结局
Medicine (Baltimore). 2019 Jul;98(27):e16156. doi: 10.1097/MD.0000000000016156.
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De novo late-onset absence status epilepticus or late-onset idiopathic generalized epilepsy? A case report and systematic review of the literature.新发晚发性失神癫痫持续状态还是晚发性特发性全身性癫痫?一例病例报告及文献系统综述。
Epileptic Disord. 2018 Apr 1;20(2):123-131. doi: 10.1684/epd.2018.0961.
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The syndrome of absence status epilepsy: review of the literature.失神性癫痫持续状态综合征:文献综述
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Epilepsia. 2005;46 Suppl 9:73-9. doi: 10.1111/j.1528-1167.2005.00316.x.
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Effect of hormones on seizure activity during pregnancy.
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