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Effect of hormones on seizure activity during pregnancy.

作者信息

Ramsay R E

出版信息

J Clin Neurophysiol. 1987 Jan;4(1):23-5. doi: 10.1097/00004691-198701000-00002.

DOI:10.1097/00004691-198701000-00002
PMID:3584436
Abstract

Increased seizure activity during pregnancy may result from two different effects: a dominant estrogenic effect early in pregnancy that directly affects the central nervous system lowering seizure threshold and a decrease of 50% or more in the plasma level of anticonvulsant drugs in some individuals late in pregnancy, resulting in loss of seizure control.

摘要

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Risk-benefit assessment of anticonvulsants in women of child-bearing potential.育龄期女性抗惊厥药物的风险效益评估。
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