Liu Ya-Tong, Zhang Qian-Qian, Yao Si-Yi, Zhao Ke-Yu, Cui Han-Wen, Zou Yue-Li, Zhao Li-Xia
Department of Chemistry, College of Arts and Sciences, Northeast Agricultural University, Harbin 150030, PR China.
Department of Chemistry, College of Arts and Sciences, Northeast Agricultural University, Harbin 150030, PR China.
Spectrochim Acta A Mol Biomol Spectrosc. 2025 Mar 15;329:125621. doi: 10.1016/j.saa.2024.125621. Epub 2024 Dec 20.
Accurately monitoring the content of Cu and Hg in real samples and biological systems is of great significance in ensuring food safety and human health. Therefore, developing efficient methods for simultaneously detecting Cu and Hg is of great significance in living organisms and real samples. In this work, a bifunctional ratiometric and colorimetric fluorescent bio-sensor DPT-1, was designed and synthesized using triphenylamine to specifically and concurrently detect Cu and Hg exhibited varying degrees of fluorescence quenching through "turn-off" fluorescence. Furthermore, DPT-1 effectively detected Cu and Hg in various real samples, encompassing tap water, Songhua River water, and honeysuckle extract. In addition, DPT-1 exhibited remarkable performance in detecting Cu/Hg in rice roots, living cells and zebrafish. As research progressed, the discoveries outlined in this article offered the versatile potential for holding promise for food safety monitoring and biological research.
准确监测实际样品和生物系统中铜和汞的含量对于确保食品安全和人类健康具有重要意义。因此，开发同时检测铜和汞的高效方法对于生物体和实际样品具有重要意义。在这项工作中，使用三苯胺设计并合成了一种双功能比率和比色荧光生物传感器DPT-1，用于特异性地同时检测铜和汞，通过“关闭”荧光表现出不同程度的荧光猝灭。此外，DPT-1有效地检测了各种实际样品中的铜和汞，包括自来水、松花江水和金银花提取物。此外，DPT-1在检测水稻根、活细胞和斑马鱼中的铜/汞方面表现出卓越的性能。随着研究的进展，本文所述的发现为食品安全监测和生物学研究提供了广阔的前景。
