Kracht Chelsea L, Harville Emily W, Cohen Nicole L, Sutton Elizabeth F, Kebbe Maryam, Redman Leanne M
Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
University of Kansas Medical Center, Kansas City, Kansas, USA.
Obesity (Silver Spring). 2025 Feb;33(2):395-404. doi: 10.1002/oby.24206. Epub 2024 Dec 25.
This study of pregnant people with obesity examined two aims in testing the hypothesis that the COVID-19 pandemic widened racial disparity in maternal health in high-risk pregnancies; it compared by race both (1) gestational weight gain (GWG) patterns and (2) patterns of preexisting conditions and adverse pregnancy outcomes.
This retrospective chart review included birth certificate and delivery records from a large women's specialty hospital in Louisiana between 2018 and 2022. Differences in preexisting conditions, GWG, and adverse pregnancy outcomes were explored across early-, peak-, and late-pandemic periods using log-linear regression and robust Poisson models.
Among 7431 deliveries (54% Black), Black pregnant people had higher rates of preexisting type 2 diabetes and chronic hypertension but lower rates of gestational diabetes and preeclampsia compared to White pregnant people across all periods. Black individuals had higher prepregnancy weight and lower GWG compared to White individuals across all periods. GWG differences were not significant in peak- and late-pandemic periods.
Black individuals with obesity started pregnancy with higher weight and more preexisting conditions but had lower GWG compared to White individuals. Exacerbated disparities in preexisting conditions demonstrate higher health risks for Black individuals during pregnancy.
本研究针对肥胖孕妇,检验了两个目标,以验证新冠疫情加剧了高危妊娠中孕产妇健康方面的种族差异这一假设;该研究按种族比较了(1)孕期体重增加(GWG)模式,以及(2)既往疾病模式和不良妊娠结局。
本回顾性病历审查纳入了2018年至2022年间路易斯安那州一家大型女子专科医院的出生证明和分娩记录。使用对数线性回归和稳健泊松模型,探讨了疫情早期、高峰期和后期在既往疾病、GWG和不良妊娠结局方面的差异。
在7431例分娩中(54%为黑人),与白人孕妇相比,黑人孕妇在所有时期的2型糖尿病和慢性高血压既往患病率较高,但妊娠期糖尿病和先兆子痫的患病率较低。在所有时期,黑人的孕前体重较高,GWG较低。在疫情高峰期和后期,GWG差异不显著。
肥胖的黑人孕妇怀孕时体重更高,存在更多既往疾病,但与白人孕妇相比,GWG较低。既往疾病方面差距的加剧表明黑人孕妇在孕期面临更高的健康风险。