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超声引导下俯卧位与仰卧位治疗近端输尿管结石冲击波碎石术的有效性和安全性:一项多中心前瞻性倾向评分匹配研究。

The effectiveness and safety between prone position and supine position for ultrasound guided shock wave lithotripsy in proximal ureteral stones: a multi-center prospective propensity score-matching study.

作者信息

Shan Liping, Liu Gang, Ge Chengshan, Guo Hongqiang, Song Shiyu, Wu Fei, Bai Song

机构信息

Department of Urology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Shenyang, Liaoning, 110004, People's Republic of China.

The Fifth Hospital of Liaoyang City, Liaoyang, China.

出版信息

World J Urol. 2024 Dec 25;43(1):46. doi: 10.1007/s00345-024-05383-6.

Abstract

BACKGROUND

Although shock wave lithotripsy (SWL) has been considered to be effective in treating ureteral stones, a definitive conclusion remains unclear on which patient's position is the optimal option for proximal ureteral stones. The purpose of this study is to assess the ideal position of ultrasound guided SWL for the treatment of proximal ureteral stones.

METHODS

This prospective study was conducted in multi-center from June 2020 to December 2023. Patients who underwent SWL in prone or supine position for proximal stones were enrolled in this study. The primary outcome was stone-free rate (SFR); the secondary outcome was complete SFR, sessions of SWL, and complications. Propensity score-matched (PSM) analysis was performed.

RESULTS

Finally, 1187 patients with proximal ureteral stones were enrolled in this study; of which 50.5% (599) were treated with prone position and 49.5% (588) underwent supine position. After 1:1 PSM, the prone position group was superior in SFR (85.7% vs. 77.4%, P = 0.001), and complete SFR (83.3% vs. 75.0%, P = 0.001) compared with the supine potion group. The sessions of SWL (1.27 vs. 1.20, P = 0.092) and complications rate (all P values > 0.05) were comparable between the two groups. In addition, the prone group had shorter skin-to-stone distance (SSD) on ultrasound than the supine group (50 mm vs. 101 mm, P < 0.001).

CONCLUSION

This multi-center prospective PSM study demonstrated that the prone position could increase the SFR and had comparable safety for ultrasound guided SWL among patients with proximal ureteral stones. Therefore, we advocate its priority application to patients with proximal ureteral stones when the prone position is possible.

摘要

背景

尽管冲击波碎石术(SWL)被认为对治疗输尿管结石有效,但对于近端输尿管结石患者的最佳体位仍未得出明确结论。本研究的目的是评估超声引导下SWL治疗近端输尿管结石的理想体位。

方法

本前瞻性研究于2020年6月至2023年12月在多中心进行。纳入在俯卧位或仰卧位接受近端结石SWL治疗的患者。主要结局是结石清除率(SFR);次要结局是完全结石清除率、SWL治疗次数和并发症。进行倾向评分匹配(PSM)分析。

结果

最终,1187例近端输尿管结石患者纳入本研究;其中50.5%(599例)采用俯卧位治疗,49.5%(588例)采用仰卧位治疗。经过1:1 PSM后,与仰卧位组相比,俯卧位组在SFR(85.7%对77.4%,P = 0.001)和完全结石清除率(83.3%对75.0%,P = 0.001)方面更具优势。两组间SWL治疗次数(1.27对1.20,P = 0.092)和并发症发生率(所有P值均>0.05)相当。此外,俯卧组超声测量的皮肤至结石距离(SSD)比仰卧组短(50 mm对101 mm,P < 0.001)。

结论

这项多中心前瞻性PSM研究表明,俯卧位可提高近端输尿管结石患者超声引导下SWL的SFR,且安全性相当。因此,我们主张在可能的情况下,优先将其应用于近端输尿管结石患者。

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