比较16种专为上消化道内镜检查设计的不同活检钳所获取标本的重量、深度及诊断充分性。
Comparison of weight, depth, and diagnostic adequacy of specimens obtained with 16 different biopsy forceps designed for upper gastrointestinal endoscopy.
作者信息
Danesh B J, Burke M, Newman J, Aylott A, Whitfield P, Cotton P B
出版信息
Gut. 1985 Mar;26(3):227-31. doi: 10.1136/gut.26.3.227.
The influence of endoscopic forceps variables (size, design, and make) on biopsy specimen weight, depth, and diagnostic adequacy has been studied in vitro on normal human stomach, and in vivo at endoscopy in dog and in patients. Greater pressure during the biopsy procedure yielded significantly heavier, deeper, and histologically more acceptable specimens. Standard sized forceps (diameter 2.4 mm) and those with ellipsoid cups consistently produced larger specimens than the smaller 'paediatric' forceps (1.8 mm) and those with round cups. Deeper specimens were also obtained using the standard forceps. In vitro and in vivo in the dog, the standard sized forceps also produced specimens of greater diagnostic adequacy than the paediatric forceps. At endoscopy in patients, however, we could not detect any influence of the size, shape, and presence of forceps spike or fenestration on the diagnostic adequacy of the specimens.
已在正常人体胃组织上进行体外研究，并在犬类和患者体内进行内镜检查，以探究内镜活检钳变量（尺寸、设计和品牌）对活检标本重量、深度和诊断充分性的影响。活检过程中施加更大压力可显著获得更重、更深且组织学上更可接受的标本。标准尺寸的活检钳（直径2.4毫米）以及杯状为椭圆形的活检钳始终比尺寸较小的“儿科”活检钳（1.8毫米）和杯状为圆形的活检钳获取的标本更大。使用标准活检钳也能获得更深的标本。在体外以及犬类体内实验中，标准尺寸的活检钳所获取标本的诊断充分性也高于儿科活检钳。然而，在对患者进行内镜检查时，我们未发现活检钳的尺寸、形状以及是否有钳尖或开窗对标本诊断充分性有任何影响。
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