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呼吸道病毒合并感染的见解。

Insights from respiratory virus co-infections.

作者信息

Georgakopoulou Vasiliki E

机构信息

Department of Pathophysiology, Laiko General Hospital, Medical School of National and Kapodistrian University of Athens, Athens 11527, Greece.

出版信息

World J Virol. 2024 Dec 25;13(4):98600. doi: 10.5501/wjv.v13.i4.98600.

Abstract

Respiratory viral co-infections present significant challenges in clinical settings due to their impact on disease severity and patient outcomes. Current diagnostic methods often miss these co-infections, complicating the epidemiology and management of these cases. Research, primarily conducted and , suggests that co-infections can lead to more severe illnesses, increased hospitalization rates, and greater healthcare utilization, especially in high-risk groups such as children, the elderly, and immunocompromised individuals. Common co-infection patterns, risk factors, and their impact on disease dynamics highlight the need for advanced diagnostic techniques and tailored therapeutic strategies. Understanding the virological interactions and immune response modulation during co-infections is crucial for developing effective public health interventions and improving patient outcomes. Future research should focus on the molecular mechanisms of co-infection and the development of specific therapies to mitigate the adverse effects of these complex infections.

摘要

呼吸道病毒合并感染在临床环境中带来了重大挑战,因为它们会影响疾病严重程度和患者预后。当前的诊断方法常常遗漏这些合并感染,使这些病例的流行病学和管理变得复杂。主要在[具体地点1]和[具体地点2]开展的研究表明,合并感染可导致更严重的疾病、更高的住院率以及更多的医疗资源利用,尤其是在儿童、老年人和免疫功能低下个体等高风险人群中。常见的合并感染模式、风险因素及其对疾病动态的影响凸显了先进诊断技术和针对性治疗策略的必要性。了解合并感染期间的病毒学相互作用和免疫反应调节对于制定有效的公共卫生干预措施和改善患者预后至关重要。未来的研究应聚焦于合并感染的分子机制以及开发特定疗法以减轻这些复杂感染的不良影响。

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