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了解系统性红斑狼疮(SLE)延迟诊断和误诊的影响。

Understanding the impact of delayed diagnosis and misdiagnosis of systemic lupus erythematosus (SLE).

作者信息

Mitchell Jordan L

机构信息

MD Candidate, Western Atlantic University School of Medicine, Freeport, Grand Bahama, The Bahamas.

出版信息

J Family Med Prim Care. 2024 Nov;13(11):4819-4823. doi: 10.4103/jfmpc.jfmpc_1177_24. Epub 2024 Nov 18.

Abstract

Systemic lupus erythematosus (SLE) is a complex and multifaceted autoimmune disease that poses a significant diagnostic challenge for healthcare providers due to its diverse clinical manifestations, lack of specific testing, and potential to mimic other conditions. Delayed diagnosis and misdiagnosis of SLE can have serious consequences for patients, impacting their physical and psychological well-being. The physical consequences of delayed diagnosis and misdiagnosis of SLE are significant. Studies have shown that delays in diagnosis can lead to increased organ damage, poorer health outcomes, and increased morbidity and mortality. With a delayed diagnosis or misdiagnosis, patients may also experience increased psychological symptoms, such as depression, anxiety, and lack of trust in clinicians. The median delay from the first symptom to diagnosis in SLE is 47 months, highlighting the need for early recognition and management. Delayed diagnosis can lead to increased disease progression, which can result in irreversible organ damage and long-term complications. This paper investigates the multifaceted consequences of delayed diagnosis and misdiagnosis of SLE, encompassing both physical and psychological impacts. It delves into the underlying reasons behind diagnostic delays and offers comprehensive strategies for healthcare providers to enhance early recognition and management. Through a thorough analysis of medical literature and statistical data, this paper aims to provide physicians with actionable insights to improve diagnostic accuracy and patient outcomes in SLE.

摘要

系统性红斑狼疮(SLE)是一种复杂且多方面的自身免疫性疾病,因其临床表现多样、缺乏特异性检测方法以及可能与其他病症相似,给医疗服务提供者带来了重大的诊断挑战。SLE的延迟诊断和误诊会给患者带来严重后果,影响他们的身心健康。SLE延迟诊断和误诊的身体后果很严重。研究表明,诊断延迟会导致器官损害增加、健康结果变差以及发病率和死亡率上升。如果诊断延迟或误诊,患者还可能出现更多的心理症状,如抑郁、焦虑以及对临床医生缺乏信任。SLE从出现首个症状到确诊的中位延迟时间为47个月,这凸显了早期识别和管理的必要性。延迟诊断会导致疾病进展加快,进而可能造成不可逆的器官损害和长期并发症。本文探讨了SLE延迟诊断和误诊的多方面后果,包括身体和心理影响。它深入研究了诊断延迟背后的根本原因,并为医疗服务提供者提供了全面的策略,以加强早期识别和管理。通过对医学文献和统计数据的深入分析,本文旨在为医生提供可行的见解,以提高SLE的诊断准确性和患者预后。

相似文献

本文引用的文献

1
Assessment of disease activity and damage in SLE: Are we there yet?SLE 疾病活动度和损伤的评估:我们做到了吗?
Best Pract Res Clin Rheumatol. 2023 Dec;37(4):101896. doi: 10.1016/j.berh.2023.101896. Epub 2023 Dec 2.
3
Pathogenesis of autoimmune disease.自身免疫性疾病的发病机制。
Nat Rev Nephrol. 2023 Aug;19(8):509-524. doi: 10.1038/s41581-023-00720-1. Epub 2023 May 10.
4
Systemic Lupus Erythematosus Classification and Diagnosis.系统性红斑狼疮分类与诊断。
Rheum Dis Clin North Am. 2021 Aug;47(3):501-511. doi: 10.1016/j.rdc.2021.04.011. Epub 2021 Jun 10.

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