Gabka J C, Baumeister R G, Liebich H G, Brendel W
Handchir Mikrochir Plast Chir. 1985 Jan;17(1):47-50.
Syngeneic and allogeneic grafts of segments of the thoracic duct from rats were investigated in the first fifteen days after transplantation. The patency rate--evaluated by the passage of blue dye--of the allogeneic transplants was almost equal to that seen in the syngeneic grafting. By direct exploration there were no changes to be seen in the syngeneic and allogeneic transplants. Investigations by electron microscopy showed no major reactions to the syngeneic grafts during the observation time: The endothelium always was completely detectable and the subendothelial layer of collagen fibrils was not dislocated. By contrast, the allogeneic transplants showed considerable alterations as disintegration of the collagen fibrils and a partial loss of endothelium occurred after eight to ten days. After fifteen days, however, the formation of a neointima could be demonstrated. Despite the observed alterations there was no loss of function in the allogeneic transplants.
在移植后的前十五天，对大鼠胸导管节段的同基因和异基因移植进行了研究。通过蓝色染料的通过来评估，异基因移植的通畅率几乎与同基因移植中观察到的通畅率相等。通过直接探查，同基因和异基因移植均未见变化。电子显微镜检查显示，在观察期内同基因移植没有重大反应：内皮始终完全可检测到，胶原纤维的内皮下层未脱位。相比之下，异基因移植显示出相当大的改变，因为八到十天后胶原纤维发生崩解且内皮部分丧失。然而，十五天后，可以证明有新内膜形成。尽管观察到有改变，但异基因移植中没有功能丧失。
