Chisesi Stefano Nicolas, Rugge Massimo, Galli Giulia Raffaella, Manni Martina, Delgado Veronica Mishell Luzuriaga, Chisesi Teodoro, Ruiz Juan Carlos, Briones Rina Mariuxi Quinto, Siculella Luisa, Guzzinati Stefano, Zorzi Manuel, Federico Massimo, Iannone Anna
Angela Serra Association for Cancer Research, Pierto Baquerizo Moreno, San Cristobal, Galapagos, Ecuador.
Department of Medicine (DIMED), Surgical Pathology and Cytopathology Unit, University of Padova, Padova, Italy.
Cancer Rep (Hoboken). 2024 Dec;7(12):e70028. doi: 10.1002/cnr2.70028.
Cancer incidence in the Galapagos archipelago is unknown.
In 2021, a task force including Ecuadorian and Italian researchers was established to estimate cancer incidence among the 25 244 Galapagos residents.
Registration covered all malignancies, including malignant melanoma and non-melanoma skin cancers; case recording was based on the International Classification of Diseases for Oncology. The data collection involved an active search across all relevant health institutions on the islands and the mainland. Mortality data were obtained from the Ecuador national mortality registry.
From January 2013 and December 2019, 174 new cancer cases were recorded, including 134 malignancies (M:F = 58:76) and 40 non-melanoma skin cancers. The mean age at diagnosis was 48 years for males and 56 years for females. Prostate, gastric, and melanocytic malignancies were most incident among males; breast, thyroid, and cervical cancers prevailed in females. The age-standardized incidence rates (ASR) were 80.39 for males and 99.24 for females with a mortality-to-incidence ratio 0.43. These ASRs were significantly lower than those reported in continental Ecuador and other South American countries.
This pilot cancer registration initiative in the Galapagos record a low incidence of malignancies and requires validation with temporal expansion of cancer registration. The environmental etiology of some of the most common cancers warrants strategic primary and secondary prevention efforts.
加拉帕戈斯群岛的癌症发病率未知。
2021年，成立了一个由厄瓜多尔和意大利研究人员组成的特别工作组，以估算加拉帕戈斯群岛25244名居民中的癌症发病率。
登记涵盖所有恶性肿瘤，包括恶性黑色素瘤和非黑色素瘤皮肤癌；病例记录依据国际肿瘤疾病分类。数据收集涉及对该群岛和大陆所有相关卫生机构进行主动搜索。死亡率数据来自厄瓜多尔国家死亡率登记处。
2013年1月至2019年12月，共记录了174例新癌症病例，其中包括134例恶性肿瘤（男：女 = 58:76）和40例非黑色素瘤皮肤癌。男性的诊断平均年龄为48岁，女性为56岁。前列腺癌、胃癌和黑素细胞恶性肿瘤在男性中最为常见；乳腺癌、甲状腺癌和宫颈癌在女性中占主导。男性的年龄标准化发病率（ASR）为80.39，女性为99.24，死亡率与发病率之比为0.43。这些ASR显著低于厄瓜多尔大陆和其他南美国家报告的发病率。
加拉帕戈斯群岛的这项癌症登记试点计划记录的恶性肿瘤发病率较低，需要随着癌症登记时间的延长进行验证。一些最常见癌症的环境病因需要进行战略性的一级和二级预防工作。
