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研究全厚皮片移植在7至14岁儿童隐匿阴茎重建中的效果。

Investigating the outcomes of full thickness skin graft in the reconstruction of concealed penis in children aged 7 to 14 years.

作者信息

Hosseinpour Mehrdad, Fazeli Ali, Moznebi Davood, Seyedyousefi Sarah

机构信息

General Surgery Department, Isfahan University of Medical Sciences, Hezar Jarib Avenue, Isfahan, Iran.

Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

BMC Urol. 2024 Dec 27;24(1):284. doi: 10.1186/s12894-024-01681-8.

DOI:10.1186/s12894-024-01681-8
PMID:39725964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11674511/
Abstract

INTRODUCTION

Concealed penis is a congenital anomaly that affects not only the appearance but also the function of the external genitalia in the male sex. Different surgical methods have been proposed to correct this disorder, including removal of the previous scar, penile shaft, penile trunk skin reconstruction with flap, penile skin fixation in penopubic and penoscrotal angles, and removal of extra pubic fat. In this study, we will discuss the results of definitive surgery in one stage using autogenous skin grafts and examine the details of this technique.

METHODS

This study was conducted as a clinical trial in Hospitals related to the Isfahan University of Medical Sciences. Children over the age of 7 years old. A full-thickness graft with a length of 1.5 times the defect and a width of 1 cm was taken from the non-dominant thigh and defatted. The inguinal skin was chosen because it is hairless and next to the penis, and the resulting scar is easily hidden under clothing. Then, the graft was transferred to the operation site and fixed.

RESULTS AND CONCLUSION

We proposed a method of treatment for concealed penis, using a full-thickness inguinal graft. Our technique showed promising results with minimal and negligible complications. To fully highlight each process's benefits and limitations and evaluate them against one another, these procedures should, however, be tested on larger populations and compared comprehensively.

TRIAL REGISTRATION

The study was conducted in accordance with the ethical standards of the Isfahan University of Medical Sciences Research Ethics Committee (ethical code: IR.MUI.MED.REC.1402.073) And was registered on 27/05/2023 as a clinical trial in Iranian registry of clinical trials. (IRCT code: IRCT20230513058160N1).

摘要

引言

隐匿阴茎是一种先天性异常,不仅影响男性外生殖器的外观,还影响其功能。已提出不同的手术方法来纠正这种疾病,包括切除先前的瘢痕、阴茎体、用皮瓣重建阴茎干皮肤、在耻骨联合和阴茎阴囊角固定阴茎皮肤以及切除耻骨上多余脂肪。在本研究中,我们将讨论使用自体皮肤移植进行一期确定性手术的结果,并研究该技术的细节。

方法

本研究作为一项临床试验在与伊斯法罕医科大学相关的医院进行。研究对象为7岁以上儿童。从非优势大腿取一块长度为缺损长度1.5倍、宽度为1厘米的全厚皮片并进行脱脂处理。选择腹股沟皮肤是因为其无毛且紧邻阴茎,术后瘢痕很容易隐藏在衣物下。然后,将皮片转移至手术部位并固定。

结果与结论

我们提出了一种使用腹股沟全厚皮片治疗隐匿阴茎的方法。我们的技术显示出了有前景的结果,并发症极少且可忽略不计。然而,为了充分突出每个过程的益处和局限性,并相互进行评估,这些手术应在更大规模的人群中进行测试并全面比较。

试验注册

本研究按照伊斯法罕医科大学研究伦理委员会的伦理标准进行(伦理代码:IR.MUI.MED.REC.1402.073),并于2023年5月27日在伊朗临床试验注册中心注册为一项临床试验(IRCT代码:IRCT20230513058160N1)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ead/11674511/ecf57e162b16/12894_2024_1681_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ead/11674511/62f5a42c1b40/12894_2024_1681_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ead/11674511/a21c15008410/12894_2024_1681_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ead/11674511/ecf57e162b16/12894_2024_1681_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ead/11674511/62f5a42c1b40/12894_2024_1681_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ead/11674511/a21c15008410/12894_2024_1681_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ead/11674511/ecf57e162b16/12894_2024_1681_Fig3_HTML.jpg

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Two levels vs. one level of phallopexy in the treatment of concealed penis in patients in pediatric age group.在儿童年龄组患者隐匿阴茎治疗中,两级阴茎固定术与一级阴茎固定术的对比
Front Pediatr. 2023 Jan 20;10:1001825. doi: 10.3389/fped.2022.1001825. eCollection 2022.
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Concealed index for concealed penis in prepubertal children.隐匿型阴茎患儿的隐匿阴茎指数。
Investig Clin Urol. 2021 Mar;62(2):217-223. doi: 10.4111/icu.20200401.
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[Comparison of pedicled skin flap of foreskin for phalloplasty and Sugita surgical method in treatment of complete concealed penis].
包皮带蒂皮瓣阴茎成形术与杉田手术方法治疗完全性隐匿阴茎的比较
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A New Surgical Technique for the Treatment of Congenital Concealed Penis Based on Anatomical Finding.基于解剖学发现的先天性隐匿阴茎治疗的新手术技术。
J Urol. 2020 Dec;204(6):1341-1348. doi: 10.1097/JU.0000000000001300. Epub 2020 Jul 27.
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[Clinical study of concealed penis correction surgery based on principle of midline symmetry].基于中线对称原则的隐匿阴茎矫正手术的临床研究
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2020 Apr 15;34(4):505-508. doi: 10.7507/1002-1892.201909106.
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[A new procedure of penoplasty for concealed penis reduces postoperative preputial edema].一种治疗隐匿阴茎的新型阴茎成形术可减轻术后包皮水肿
Zhonghua Nan Ke Xue. 2019 Oct;25(10):901-904.
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