• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

颈项强直的罕见病因:累及颅骨和上颈椎的转移性三阴性乳腺癌

A Rare Cause of Nuchal Rigidity: Metastatic Triple-Negative Breast Cancer Involving the Skull and Upper Cervical Spine.

作者信息

Katkov Daniil

机构信息

Internal Medicine, Waterbury Hospital, Waterbury, USA.

出版信息

Cureus. 2024 Nov 26;16(11):e74490. doi: 10.7759/cureus.74490. eCollection 2024 Nov.

DOI:10.7759/cureus.74490
PMID:39726494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11671049/
Abstract

A 48-year-old female presented to the ED with worsening headache and neck pain for the past week. Her medical history is significant for recurrent left-sided triple-negative breast cancer (TNBC) with metastasis to the chest wall, liver, and lungs, initially diagnosed two years ago. She underwent a left-sided mastectomy and received radiation therapy and chemotherapy. Physical examination was remarkable for nuchal rigidity and photophobia. MRI of the brain with contrast was performed, and the results were consistent with the new calvarium, skull, and upper cervical spine osseous metastases without any intracranial metastatic disease. This case report presents a rare cause of nuchal rigidity and photophobia due to an uncommon metastatic pattern in a patient with TNBC.

摘要

一名48岁女性因过去一周头痛和颈部疼痛加重而就诊于急诊科。她的病史主要为两年前初诊的复发性左侧三阴性乳腺癌(TNBC),已转移至胸壁、肝脏和肺部。她接受了左侧乳房切除术,并接受了放疗和化疗。体格检查发现有颈项强直和畏光现象。进行了脑部增强MRI检查,结果显示符合新的颅骨、头骨和上颈椎骨转移,无任何颅内转移疾病。本病例报告展示了一名TNBC患者因罕见的转移模式导致颈项强直和畏光的罕见病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6276/11671049/7a246bd963e8/cureus-0016-00000074490-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6276/11671049/4993803860b0/cureus-0016-00000074490-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6276/11671049/7a246bd963e8/cureus-0016-00000074490-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6276/11671049/4993803860b0/cureus-0016-00000074490-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6276/11671049/7a246bd963e8/cureus-0016-00000074490-i02.jpg

相似文献

1
A Rare Cause of Nuchal Rigidity: Metastatic Triple-Negative Breast Cancer Involving the Skull and Upper Cervical Spine.颈项强直的罕见病因:累及颅骨和上颈椎的转移性三阴性乳腺癌
Cureus. 2024 Nov 26;16(11):e74490. doi: 10.7759/cureus.74490. eCollection 2024 Nov.
2
Leptomeningeal Carcinomatosis: A Case Report of Metastatic Triple-negative Breast Adenocarcinoma.柔脑膜癌病:转移性三阴性乳腺腺癌病例报告
Cureus. 2019 Mar 19;11(3):e4278. doi: 10.7759/cureus.4278.
3
Case report of long-term survival with metastatic triple-negative breast carcinoma: Treatment possibilities for metastatic disease.转移性三阴性乳腺癌长期生存病例报告:转移性疾病的治疗可能性
Medicine (Baltimore). 2019 Apr;98(16):e15302. doi: 10.1097/MD.0000000000015302.
4
Can we cure stage IV triple-negative breast carcinoma?: Another case report of long-term survival (7 years).我们能治愈IV期三阴性乳腺癌吗?:另一例长期生存(7年)的病例报告。
Medicine (Baltimore). 2019 Sep;98(38):e17251. doi: 10.1097/MD.0000000000017251.
5
Paraneoplastic Encephalopathy in a Patient With Metastatic Lung Cancer: A Case Study.一名转移性肺癌患者的副肿瘤性脑病:病例报告
J Adv Pract Oncol. 2018 Mar;9(2):216-221. Epub 2018 Mar 1.
6
Neoplastic cerebral aneurysm from triple-negative breast cancer: A case report.三阴性乳腺癌所致的肿瘤性脑动脉瘤:一例报告
Surg Neurol Int. 2021 May 3;12:204. doi: 10.25259/SNI_74_2021. eCollection 2021.
7
Management of refractory metastatic anal squamous cell carcinoma following disease progression on traditional chemoradiation therapy.传统放化疗治疗后疾病进展的难治性转移性肛管鳞状细胞癌的管理
J Adv Pract Oncol. 2012 May;3(3):161-9. doi: 10.6004/jadpro.2012.3.3.4.
8
Human epidermal growth factor receptor 2-positive metastatic breast cancer with novel epidermal growth factor receptor -ZNF880 fusion and epidermal growth factor receptor E114K mutations effectively treated with pyrotinib: A case report.人表皮生长因子受体 2 阳性转移性乳腺癌伴新型表皮生长因子受体-ZNF880 融合和表皮生长因子受体 E114K 突变,吡咯替尼治疗有效:一例报告。
Medicine (Baltimore). 2020 Dec 18;99(51):e23406. doi: 10.1097/MD.0000000000023406.
9
Current and Emerging Therapies for HER2-Positive Women With Metastatic Breast Cancer.HER2阳性转移性乳腺癌女性的当前及新出现的治疗方法
J Adv Pract Oncol. 2017 Mar;8(2):164-168. Epub 2017 Mar 1.
10
Breast cancer metastases to the thyroid gland - an uncommon sentinel for diffuse metastatic disease: a case report and review of the literature.乳腺癌转移至甲状腺——弥漫性转移性疾病的罕见前哨:一例病例报告及文献综述
J Med Case Rep. 2017 Sep 22;11(1):269. doi: 10.1186/s13256-017-1441-x.

本文引用的文献

1
Overall Survival and Prognostic Factors in Metastatic Triple-Negative Breast Cancer: A National Cancer Database Analysis.转移性三阴性乳腺癌的总生存期及预后因素:一项国家癌症数据库分析
Cancers (Basel). 2024 May 8;16(10):1791. doi: 10.3390/cancers16101791.
2
Bone Metastasis of Breast Cancer: Molecular Mechanisms and Therapeutic Strategies.乳腺癌骨转移:分子机制与治疗策略
Cancers (Basel). 2022 Nov 22;14(23):5727. doi: 10.3390/cancers14235727.
3
Advances in the Diagnosis and Treatment of Leptomeningeal Disease.脑膜疾病的诊断与治疗进展。
Curr Neurol Neurosci Rep. 2022 Jul;22(7):413-425. doi: 10.1007/s11910-022-01198-3. Epub 2022 May 19.
4
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
5
Understanding the Bone in Cancer Metastasis.理解癌症转移中的骨骼。
J Bone Miner Res. 2018 Dec;33(12):2099-2113. doi: 10.1002/jbmr.3618. Epub 2018 Nov 26.
6
Molecular Regulation of Bone Metastasis Pathogenesis.骨转移发病机制的分子调控
Cell Physiol Biochem. 2018;46(4):1423-1438. doi: 10.1159/000489184. Epub 2018 Apr 18.
7
Incidence, pattern and prognosis of brain metastases in patients with metastatic triple negative breast cancer.转移性三阴性乳腺癌患者脑转移的发生率、模式和预后。
BMC Cancer. 2018 Apr 19;18(1):446. doi: 10.1186/s12885-018-4371-0.
8
Surgical treatment of upper cervical spine metastases: a retrospective study of 39 cases.上颈椎转移瘤的外科治疗:39例回顾性研究
World J Surg Oncol. 2017 Jan 14;15(1):21. doi: 10.1186/s12957-016-1085-0.
9
Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease.三阴性乳腺癌:一种异质性疾病的挑战与机遇
Nat Rev Clin Oncol. 2016 Nov;13(11):674-690. doi: 10.1038/nrclinonc.2016.66. Epub 2016 May 17.
10
Shedding light on photophobia.揭示畏光现象。
J Neuroophthalmol. 2012 Mar;32(1):68-81. doi: 10.1097/WNO.0b013e3182474548.