Parliament M B, Danjoux C E, Clayton T
Int J Radiat Oncol Biol Phys. 1985 Mar;11(3):603-8. doi: 10.1016/0360-3016(85)90195-6.
To assess current documentation of treatment-related toxicity, 46 out-patients attending the Ottawa Civic Hospital Cancer Clinic were randomly selected. Physician's charting of toxicities was compared to patient's perception of toxicity, as recorded on a brief questionnaire. As a group, patients reported significantly more toxicities than had been recorded by their physician. The greatest disparity was observed for the following categories: nausea, vomiting, alopecia, and decreased performance status. The best-documented toxicities were: skin and mucosal reactions, and urinary symptoms. To the question concerning their most bothersome symptoms, patients described nausea, vomiting, mucosal reaction, and decreased performance status as the most common. In 46% of cases, the physician's notes failed to identify the patient's worst symptom. From our study; toxicity is probably under-reported, and unrecognized by oncologists. A self-administered questionnaire appears to be a better way of accurately identifying and reporting treatment toxicities, when compared to the oncologist's evaluation, as recorded in the patient's permanent record.
为评估当前与治疗相关毒性的记录情况，从渥太华市民医院癌症诊所就诊的46名门诊患者中随机选取。将医生对毒性的记录与患者在一份简短问卷中记录的对毒性的感知进行比较。总体而言，患者报告的毒性显著多于医生记录的毒性。在以下类别中观察到最大差异：恶心、呕吐、脱发和身体状况下降。记录最完善的毒性是：皮肤和黏膜反应以及泌尿系统症状。对于关于他们最困扰症状的问题，患者将恶心、呕吐、黏膜反应和身体状况下降描述为最常见的。在46%的病例中，医生的记录未能识别出患者最严重的症状。根据我们的研究，毒性可能报告不足，且未被肿瘤学家认识到。与记录在患者永久病历中的肿瘤学家评估相比，自我管理的问卷似乎是准确识别和报告治疗毒性的更好方法。
