Fraass B A, Kinsella T J, Harrington F S, Glatstein E
Int J Radiat Oncol Biol Phys. 1985 Mar;11(3):609-15. doi: 10.1016/0360-3016(85)90196-8.
A simple and practical gonadal shield has been developed for use near megavoltage radiation fields. The lead shield encloses only the testes, allowing its use with nearly any radiation field that does not include the testes. The dose to the testes with and without the shield has been measured extensively both in phantoms and on patients. The gonadal shield allows a 3 to 10-fold reduction in dose to the testes depending primarily on the distance from the field edge to the gonads. When the shield is used, the gonadal dose is always less than 1% of the patient's prescription dose. Based on our patient studies of testicular injury following conventionally-fractionated irradiation, a dose of less than 50 cGy (1% of a typical 5000 cGy treatment regimen) should preserve normal testicular function.
一种简单实用的性腺防护装置已被开发出来，用于兆伏级辐射野附近。铅制防护装置仅包围睾丸，使其可用于几乎任何不包括睾丸的辐射野。有无防护装置时睾丸所受剂量已在体模和患者身上进行了广泛测量。性腺防护装置可使睾丸所受剂量降低3至10倍，这主要取决于从射野边缘到性腺的距离。使用防护装置时，性腺剂量始终低于患者处方剂量的1%。根据我们对常规分割照射后睾丸损伤的患者研究，剂量低于50 cGy（典型的5000 cGy治疗方案的1%）应能保留正常睾丸功能。
