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新型自组装肽和树脂浸润引导牙釉质再生对不同挑战下人工牙釉质病变的颜色掩盖能力:一项体外分光光度分析

Color Masking Ability of Guided Enamel Regeneration with a Novel Self-Assembling Peptide and Resin Infiltration on Artificial Enamel Lesions Under Various Challenges: An In Vitro Spectrophotometric Analysis.

作者信息

Albar Nassreen, Basheer Syed Nahid, Moaleem Mohammed M Al, Ageel Sana, Abbas Rehab, Hakami Rafaa, Daghrery Arwa, Sawady Mohammed, Peeran Syed Wali, Vinothkumar Thilla Sekar, Zidane Bassam

机构信息

Department of Restorative Dental Sciences, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.

Department of Prosthetic Dental Sciences, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.

出版信息

Biomimetics (Basel). 2024 Dec 16;9(12):764. doi: 10.3390/biomimetics9120764.

DOI:10.3390/biomimetics9120764
PMID:39727768
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11673875/
Abstract

The color masking ability of resin infiltration (RI) and curodont repair fluoride plus-self-assembling peptide (CRFP-SAP) was investigated under various simulated oral challenging conditions. Sixty-four extracted caries-free human canines were randomly divided into two groups: Group 1 (RI) and Group 2 (CRFP-SAP). The baseline color values of samples were recorded using a spectrophotometer (VITA Easyshade Advance 4.0 VITA Zahnfabrik, Bad Sackingen, Germany). The samples were stored in a demineralization solution for 4 days to induce artificial enamel lesions (AELs). The AELs of Groups I and II were treated with RI (Icon, DMG, Hamburg, Germany) and CRFP-SAP (vVARDIS, Zug, Switzerland), respectively, followed by color measurements. Each group was subjected to challenges such as remineralization, pH cycling, staining, and thermocycling, followed by color measurements. The difference between the mean ∆E (color difference value) of sound enamel and both treatment groups was less than 3.7 1-week post treatment. Meanwhile, the difference between the mean ∆E of RI-treated samples and all kinds of challenges was more than 3.7, while for the CRFP-SAP-treated samples, it was less than 3.7 for all kinds of challenges, except for the thermocycling, for which the mean ∆E difference was 4.3. RI and CRFP-SAP treatments were effective in masking the discoloration caused by AELs. However, the color was not stable for RI-treated samples, whereas it was stable for CRFP-SAP-treated samples under all challenges, except for thermocycling.

摘要

在各种模拟口腔挑战条件下,研究了树脂渗透(RI)和含氟自组装肽的龋洞修复材料(CRFP-SAP)的颜色掩盖能力。64颗拔除的无龋人类犬齿被随机分为两组:第1组(RI)和第2组(CRFP-SAP)。使用分光光度计(VITA Easyshade Advance 4.0,德国巴德萨克京的VITA Zahnfabrik公司)记录样本的基线颜色值。将样本储存在脱矿溶液中4天以诱导人工釉质病变(AELs)。第I组和第II组的AELs分别用RI(Icon,德国汉堡的DMG公司)和CRFP-SAP(瑞士楚格的vVARDIS公司)处理,随后进行颜色测量。每组都要经历再矿化、pH循环、染色和热循环等挑战,然后进行颜色测量。治疗后1周,健康釉质与两个治疗组的平均∆E(颜色差值)之间的差异小于3.7。同时,RI处理样本与各种挑战之间的平均∆E差异大于3.7,而对于CRFP-SAP处理的样本,除热循环外,各种挑战下的平均∆E差异均小于3.7,热循环的平均∆E差异为4.3。RI和CRFP-SAP处理在掩盖AELs引起的变色方面是有效的。然而,RI处理样本的颜色不稳定,而CRFP-SAP处理样本在除热循环外的所有挑战下颜色都稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dee/11673875/06d94b43babc/biomimetics-09-00764-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dee/11673875/13c5e1d765af/biomimetics-09-00764-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dee/11673875/1313c887beec/biomimetics-09-00764-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dee/11673875/cfe799ee4e18/biomimetics-09-00764-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dee/11673875/06d94b43babc/biomimetics-09-00764-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dee/11673875/13c5e1d765af/biomimetics-09-00764-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dee/11673875/1313c887beec/biomimetics-09-00764-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dee/11673875/cfe799ee4e18/biomimetics-09-00764-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dee/11673875/06d94b43babc/biomimetics-09-00764-g004.jpg

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本文引用的文献

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BMC Oral Health. 2024 Jul 30;24(1):868. doi: 10.1186/s12903-024-04523-z.
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The Effect of Non-Invasive Treatment Techniques on the Color Masking Ability and Surface Roughness of Induced Enamel Lesions (An Study).非侵入性治疗技术对诱导性釉质病变颜色遮盖能力和表面粗糙度的影响(一项研究)
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Biomimetic Remineralization of Artificial Caries Lesions with a Calcium Coacervate, Its Components and Self-Assembling Peptide P-4 In Vitro.
用钙凝聚层、其成分及自组装肽P-4对人工龋损进行体外仿生再矿化
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