Herrera Jerez M J, Castro-Peraza M E, Delgado Morales N M, Arias Rodriguez A
Doctoral Program in Medical and Pharmaceutical Sciences, Development and Quality of Life, University of La Laguna, 38200 Santa Cruz de Tenerife, Spain.
University Hospital of the Canary Islands, Canary Islands Health Service, 38320 Santa Cruz de Tenerife, Spain.
Nurs Rep. 2024 Dec 20;14(4):4109-4118. doi: 10.3390/nursrep14040299.
Hormone blockers are defined as substances that suppress the release of sex hormones, thus inhibiting the development of secondary sexual characteristics in teenagers. There is currently an increase in young people seeking healthcare services due to a mismatch between their birth-assigned gender and their perceived or self-identified gender. In early childhood, individuals are not usually affected by their physical appearance. Dysphoria may arise during the initial stages of adolescence and if the self-perceived gender does not align with the external appearance. This may have a negative impact on adolescents' mental health. Could the use of hormone blockers have a positive effect on mental health? The primary objective of this review is to assess whether the use of hormone blockers can have positive effects on the mental health of transgender youth. The review also seeks to evaluate the usage of hormone blockers and the diagnosis of gender dysphoria. A literature search of scientific evidence was conducted across various databases-PUBMED, CUIDEN, ELSEVIER, COCHRANE, DIMENSIONS, SCIELO, PSYCINFO, and CINAHL-alongside a review of the latest publications in high-impact scientific journals and the gray literature. The following terms were used:
激素阻断剂被定义为抑制性激素释放的物质，从而抑制青少年第二性征的发育。目前，由于出生时被指定的性别与他们所感知或自我认同的性别不匹配，寻求医疗服务的年轻人有所增加。在幼儿期，个体通常不会受到其外貌的影响。烦躁不安可能在青春期初期出现，如果自我感知的性别与外在表现不一致。这可能会对青少年的心理健康产生负面影响。使用激素阻断剂会对心理健康产生积极影响吗？本综述的主要目的是评估使用激素阻断剂是否会对跨性别青少年的心理健康产生积极影响。该综述还旨在评估激素阻断剂的使用情况以及性别烦躁症的诊断。我们在多个数据库——PubMed、Cuiden、Elsevier、Cochrane、Dimensions、SciELO、PsycINFO和CINAHL——中进行了科学证据的文献检索，同时还查阅了高影响力科学期刊和灰色文献中的最新出版物。使用了以下术语：<跨性别者>、<激素阻断剂>、<抑郁症>、<焦虑症>、<青少年>、<跨性别青少年>和<烦躁不安>。指定了一个时间段，涵盖过去十年（2014 - 2024年）。初步搜索共识别出290篇参考文献，随后缩小至5项研究，通过其他方法又检索到1项研究。文献研究结果很明确。它们表明，在跨性别青少年中使用激素阻断剂可能是有益的，因为在使用期间及之后观察到心理健康问题有所减少。跨性别青少年的心理保健对他们的身体、心理、社会和学业领域至关重要。对他们的家庭也非常重要。护士必须了解这些知识，以便在围绕使用激素阻断剂的决策这一困难时期，改善为这些个体及其家庭提供的护理。
