Mohapatra Monalisa, Tibrewal Shailja, Chatterjee Samrat, Agarwal Pradeep, Shah Chintan, Kapoor Rajat, Sahoo Anupam, Sen Pradhanya, Maan Veenu, Shetty Sonu Arjun, Sutar Samir, Goyal Priya, Ganesh Suma
Paediatric Ophthalmology Services, MGM Eye Institute, Raipur, Chhattisgarh, India.
The Bodhya Eye Consortium, India.
Indian J Ophthalmol. 2025 Mar 1;73(3):335-340. doi: 10.4103/IJO.IJO_607_24. Epub 2024 Dec 27.
To study the clinical profile of patients with microspherophakia and the factors associated with poor vision following lensectomy surgery.
A multicenter, retrospective, cross-sectional analysis was conducted from January 2010 to June 2022 on patients diagnosed with microspherophakia.
A total of 102 eyes from 51 patients were enrolled, of whom 24 (47.1%) were male and 27 (52.9%) were female. All patients presented with bilateral involvement. The most common presenting complaint was defective vision, affecting 98 (96.1%) eyes. Patients exhibited varying degrees of lenticular myopia, with a mean refractive error of -13.54 ± 11.92 D. Glaucoma was present in 36 (35.3%) eyes at presentation. Subluxation of the crystalline lens was observed in 50 (49.1%) eyes, dislocation of the lens into the anterior chamber in 24 (23.5%) eyes, and dislocation into the vitreous cavity in 4 (3.9%) eyes. Limbal or pars plana lensectomy was performed in 54 (52.9%) eyes. The mean corrected visual acuity improved from 1.05 ± 0.82 logMAR units to 0.82 ± 0.79 logMAR units after lensectomy ( P = 0.029). Poor postoperative visual acuity (less than 20/200) was associated with poor preoperative visual acuity ( P = 0.005), presence of glaucoma at the first visit ( P = 0.013), and intraocular pressure >30 mmHg ( P < 0.001).
Microspherophakia is associated with high lenticular myopia, subluxation, and dislocation of the crystalline lens. Significant improvement in postoperative vision was observed after lensectomy. Factors associated with poor postoperative vision included poor preoperative corrected vision, presence of glaucoma, and high intraocular pressure.
研究小球形晶状体患者的临床特征以及晶状体切除术后视力不佳的相关因素。
对2010年1月至2022年6月期间诊断为小球形晶状体的患者进行了多中心、回顾性横断面分析。
共纳入51例患者的102只眼，其中男性24例（47.1%），女性27例（52.9%）。所有患者均为双眼受累。最常见的主诉是视力缺陷，累及98只眼（96.1%）。患者表现出不同程度的晶状体性近视，平均屈光不正为-13.54±11.92D。就诊时36只眼（35.3%）存在青光眼。50只眼（49.1%）观察到晶状体半脱位，24只眼（23.5%）晶状体脱位至前房，4只眼（3.9%）脱位至玻璃体腔。54只眼（52.9%）进行了角膜缘或睫状体平坦部晶状体切除术。晶状体切除术后平均矫正视力从1.05±0.82logMAR单位提高到0.82±0.79logMAR单位（P=0.029）。术后视力不佳（低于20/200）与术前视力不佳（P=0.005）、初诊时存在青光眼（P=0.013）以及眼压>30mmHg（P<0.001）相关。
小球形晶状体与高度晶状体性近视、晶状体半脱位和脱位有关。晶状体切除术后观察到术后视力有显著改善。与术后视力不佳相关的因素包括术前矫正视力差、存在青光眼和高眼压。
