Dong Juan, Ma Xumin, Hu Xingxin, Yan Mengmeng
Southwest Medical University, Luzhou, China.
Meishan Cancer Hospital, Meishan, China.
PLoS One. 2024 Dec 27;19(12):e0316023. doi: 10.1371/journal.pone.0316023. eCollection 2024.
Few studies have globally assessed the cardiovascular disease (CVD) mortality burden attributable to secondhand smoke. We aimed to address this research gap.
We used a systematic analysis design using data from the Global Burden of Disease Study 2019. Our primary outcome measures were the age-standardized mortality rate (ASMR) and age-standardized disability-adjusted life years (DALYs) for CVD attributable to secondhand smoke. The annual average percentage change (AAPC) was utilized to describe the temporal trends of ASMR and DALYs.
From 1990 to 2019, global ASMR for CVD due to secondhand smoke decreased from 11.45 (95% CI: 9.47 to 13.42) to 7.43 (95% CI: 6.09 to 8.85), and DALYs decreased from 274.12 (95% CI: 225.36 to 322.20) to 176.93 (95% CI: 145.21 to 211.28). ASMR and DALYs attributable to secondhand smoke are on the rise in 47 countries, with 18 of these countries experiencing increases across both genders and all cardiovascular subtypes. Uzbekistan, Lesotho, and the Philippines have the highest AAPC for CVD due to secondhand smoke in ASMR and DALYs. Specifically, Uzbekistan's overall ASMR AAPC is 2.2 (95%CI: 2.1-2.3), Lesotho's is 1.3 (95%CI: 1.2-1.3), and the Philippines' is 1.1 (95%CI: 1.0-1.2). In terms of DALYs, the AAPC values are 1.7 for Uzbekistan (95%CI: 1.7-1.8), 1.4 for Lesotho (95%CI: 1.3-1.5), and 1.8 for the Philippines (95%CI: 1.7-1.9).
Over the past three decades, the epidemiological landscape of CVD mortality associated with secondhand smoke has undergone significant shifts. Notwithstanding global advancements, intensified interventions are paramount in regions experiencing ascending rates.
很少有研究全面评估二手烟导致的心血管疾病（CVD）死亡负担。我们旨在填补这一研究空白。
我们采用系统分析设计，使用来自《2019年全球疾病负担研究》的数据。我们的主要结局指标是二手烟导致的心血管疾病的年龄标准化死亡率（ASMR）和年龄标准化伤残调整生命年（DALYs）。年度平均百分比变化（AAPC）用于描述ASMR和DALYs的时间趋势。
从1990年到2019年，全球二手烟导致的心血管疾病的ASMR从11.45（95%CI：9.47至13.42）降至7.43（95%CI：6.09至8.85），DALYs从274.12（95%CI：225.36至322.20）降至176.93（95%CI：145.21至211.28）。47个国家中，二手烟导致的ASMR和DALYs呈上升趋势，其中18个国家的男性和女性以及所有心血管亚型均出现上升。乌兹别克斯坦、莱索托和菲律宾二手烟导致的心血管疾病的ASMR和DALYs的AAPC最高。具体而言，乌兹别克斯坦的总体ASMR的AAPC为2.2（95%CI：2.1-2.3），莱索托为1.3（95%CI：1.2-1.3），菲律宾为1.1（95%CI：1.0-1.2）。就DALYs而言，乌兹别克斯坦的AAPC值为1.7（95%CI：1.7-1.8），莱索托为1.4（95%CI：1.3-1.5），菲律宾为1.8（95%CI：1.7-1.9）。
在过去三十年中，与二手烟相关的心血管疾病死亡的流行病学格局发生了重大变化。尽管全球取得了进展，但在发病率上升的地区加强干预至关重要。
