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袋鼠式护理用于早产和低出生体重婴儿转运的可行性:加纳海岸角新生儿转运的双臂非随机对照整群可行性研究

Feasibility of the use of Kangaroo mother care in the transfer of preterm and low-birth-weight infants: a two-arm nonrandomized controlled cluster feasibility study of neonatal transport in Cape Coast, Ghana.

作者信息

Okai Emmanuel, Fair Frankie, Konadu Hilda Danquah, Darteh Eugene K M, Soltani Hora

机构信息

Department of Paediatrics and Child Health, School of Medical Sciences, College of Health and Allied Sciences, University of Cape Coast, PMB, Cape Coast, Ghana.

Department of Paediatrics and Child Health, Cape Coast Teaching Hospital, Cape Coast, Ghana.

出版信息

BMC Pediatr. 2024 Dec 28;24(1):842. doi: 10.1186/s12887-024-05340-7.

Abstract

BACKGROUND

Despite progress made towards SDG 3, sub-Saharan Africa lags behind the rest of the world, accounting for over 50% of global neonatal deaths. The increased number of hospital births in the region has not reciprocated the reduction in neonatal mortality rates. Sick newborns face uncertain journeys from peripheral facilities to specialized centres arriving in suboptimal conditions, which impacts their outcomes, due partly to the scarcity of dedicated neonatal transport services.

METHODS

This was a 2-arm nonrandomized controlled cluster study of preterm and low-birth-weight neonates transferred from eight peripheral sites to a tertiary neonatal unit via conventional methods or the KMC (August 2022-April 2023).

RESULTS

A total of 77 (mother-baby pairs) were recruited, 34 in the KMC group and 43 in the conventional arm. Most (60%) were transported by taxis/private cars. Overall mortality was 20.8%. No untoward event was recorded for neonates transported by KMC, with marginally better temperatures on arrival. Although the observed differences were not statistically significant given that this was not the primary aim, the findings add to evidence that KMC transport may not be more life-threatening than the current practice of transporting newborns in the caregiver's arms. KMC transport has the added advantage of ensuring non-separation of the small and sick child from its mother from birth and improved temperatures upon arrival.

CONCLUSION

KMC transport for preterm and Low birth weight infants using available transport in Sub-Saharan Africa is feasible. Local large-scale randomized trials are needed to gather more evidence for policy direction needed to inform a scale-up of this low-cost intervention.

TRIAL REGISTRATION

ISRCTN98748162. Retrospectively registered 02.09.2024.

摘要

背景

尽管在实现可持续发展目标3方面取得了进展,但撒哈拉以南非洲地区仍落后于世界其他地区,占全球新生儿死亡人数的50%以上。该地区医院分娩数量的增加并未带来新生儿死亡率的相应下降。患病新生儿从周边医疗机构转运至专科中心的过程充满不确定性,到达时状况不佳,这影响了他们的治疗结果,部分原因是缺乏专门的新生儿转运服务。

方法

这是一项双臂非随机对照整群研究,研究对象为2022年8月至2023年4月期间从八个周边地点通过传统方法或袋鼠式护理(KMC)转运至三级新生儿病房的早产和低体重新生儿。

结果

共招募了77对母婴,袋鼠式护理组34对,传统组43对。大多数(60%)是乘坐出租车/私家车转运的。总体死亡率为20.8%。接受袋鼠式护理转运的新生儿未记录到不良事件,到达时体温略好。鉴于这并非主要目的,观察到的差异无统计学意义,但这些发现进一步证明,袋鼠式护理转运可能并不比目前将新生儿抱在护理人员怀中转运的做法更具生命威胁性。袋鼠式护理转运还有一个额外的优势,即能确保患病的小婴儿从出生起就不与母亲分离,且到达时体温有所改善。

结论

在撒哈拉以南非洲地区,利用现有交通工具对早产和低体重婴儿进行袋鼠式护理转运是可行的。需要进行当地大规模随机试验,以收集更多证据,为扩大这种低成本干预措施所需的政策方向提供依据。

试验注册

ISRCTN98748162。于2024年9月2日进行回顾性注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1daa/11681684/0df97d7b07a5/12887_2024_5340_Fig1_HTML.jpg

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