Suppr超能文献

埃塞俄比亚亚的斯亚贝巴治疗心血管疾病基本药物的可及性、价格及可负担性

Availability, price and affordability of essential medicines for managing cardiovascular disease in Addis Ababa, Ethiopia.

作者信息

Masresha Rediet, Habte Fikreselam, Senbeta Mamo Feyissa, Baye Assefa Mulu, Kassaw Chalelgn, Beyene Melak Gedamu

机构信息

School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

出版信息

Sci Rep. 2024 Dec 28;14(1):31357. doi: 10.1038/s41598-024-82919-1.

Abstract

Access to health care is a fundamental human right. However, nearly one-third of the global population have no access to it. This magnitude is even much worse in low- and middle-income countries. A cross-sectional study was conducted from April 12 to June 5, 2024 to determine availability, price and affordability of essential medicines for managing cardiovascular diseases using WHO/HAI methodology in Addis Ababa, Ethiopia. Data on the availability and price of the lowest priced generic medicines were collected from five public, ten private and eight other sectors in Addis Ababa, Ethiopia. The availability was assessed as the percentage of health facilities that stocked the listed medicines. The prices of these medicines were evaluated across all sectors. Price variations were calculated to identify differences among these settings. Additionally, medicine prices were compared against the management sciences for health (MSH) International Reference Prices to calculate the Median Price Ratio (MPR), providing a standardized measure of price affordability and accessibility. The data was analyzed using WHO/HAI work book Excel sheet V 15. The overall availability of generic drugs in all sectors was found to be 34.52%. The availability was 33.73, 40.58, 29.8 and 33.99% in Public, Private, Kenema and Red Cross pharmacies, respectively. The median price ratios for the medications used to treat cardiovascular disease were 3.49, 7.24, 2.84 and 5.2 at Public, Private, Kenema, and Red Cross Pharmacies, respectively. Majority of the medicines were found to be unaffordable, costing up to 352.44 days' wage of the lowest paid government employee to cover a one-month standard treatment. In conclusion, the study underscores significant challenges in the availability, pricing, and affordability of LPG medications to treat CVDs in Ethiopia.

摘要

获得医疗保健是一项基本人权。然而,全球近三分之一的人口无法获得医疗保健。在低收入和中等收入国家,这一情况更为严重。2024年4月12日至6月5日,在埃塞俄比亚亚的斯亚贝巴开展了一项横断面研究,采用世界卫生组织/卫生行动干预与费用追踪(WHO/HAI)方法,以确定用于治疗心血管疾病的基本药物的可获得性、价格和可负担性。从埃塞俄比亚亚的斯亚贝巴的5家公立、10家私立及8家其他机构收集了最低价格仿制药的可获得性和价格数据。可获得性通过储存所列药品的医疗机构的百分比来评估。对所有机构的这些药品价格进行了评估。计算价格差异以确定这些机构之间的差异。此外,将药品价格与健康管理科学(MSH)国际参考价格进行比较,以计算中位数价格比(MPR),从而提供价格可负担性和可及性的标准化衡量指标。使用WHO/HAI工作簿Excel工作表V 15对数据进行了分析。所有机构中仿制药的总体可获得性为34.52%。在公立、私立、凯内马药房和红十字会药房的可获得性分别为33.73%、40.58%、29.8%和33.99%。用于治疗心血管疾病的药物在公立、私立、凯内马和红十字会药房的中位数价格比分别为3.49、7.24、2.84和5.2。发现大多数药品难以负担,支付一个月标准治疗费用高达最低工资政府雇员352.44天的工资。总之,该研究强调了埃塞俄比亚治疗心血管疾病的低价仿制药在可获得性、定价和可负担性方面面临的重大挑战。

相似文献

3
Availability, price, and affordability of antiseizure medicines in Addis Ababa, Ethiopia.
Epilepsia Open. 2023 Sep;8(3):1123-1132. doi: 10.1002/epi4.12792. Epub 2023 Jul 28.
6
Evaluation of availability, price, and affordability of cardiovascular, diabetes, and global medicines in Abuja, Nigeria.
PLoS One. 2021 Aug 12;16(8):e0255567. doi: 10.1371/journal.pone.0255567. eCollection 2021.
9
Price, Availability and Affordability of Anti-Cancer Medicines in Addis Ababa, Ethiopia.
Risk Manag Healthc Policy. 2022 Dec 29;15:2421-2433. doi: 10.2147/RMHP.S395456. eCollection 2022.
10
Availability, Price and Affordability of Psychotropic Medicines in Addis Ababa, Ethiopia.
Risk Manag Healthc Policy. 2023 May 22;16:957-970. doi: 10.2147/RMHP.S409929. eCollection 2023.

引用本文的文献

1
An overview of the association between socioeconomic deprivation and heart failure.
Heart Fail Rev. 2025 Aug 12. doi: 10.1007/s10741-025-10550-x.

本文引用的文献

1
Factors Affecting the Availability and Utilization of Essential Medicines in India: A Systematic Review.
J Pharm Bioallied Sci. 2024 Apr;16(Suppl 2):S1064-S1071. doi: 10.4103/jpbs.jpbs_1198_23. Epub 2024 Apr 16.
2
Medicines prices in International (Geary-Khamis) Dollar. The comparison between regulated and deregulated markets.
PLoS One. 2024 Jun 7;19(6):e0304400. doi: 10.1371/journal.pone.0304400. eCollection 2024.
3
Barriers to accessibility of medicines for hyperlipidemia in low- and middle-income countries.
PLOS Glob Public Health. 2024 Feb 12;4(2):e0002905. doi: 10.1371/journal.pgph.0002905. eCollection 2024.
4
A systematic scoping review of medicine availability and affordability in Africa.
BMC Health Serv Res. 2024 Jan 17;24(1):91. doi: 10.1186/s12913-023-10494-8.
5
Health as a Human Right: A Position Paper From the American College of Physicians.
Ann Intern Med. 2023 Nov;176(11):1516-1519. doi: 10.7326/M23-1900. Epub 2023 Oct 31.
6
Global Barriers to Accessing Off-Patent Endocrine Therapies: A Renaissance of the Orphan Disease?
J Clin Endocrinol Metab. 2024 Apr 19;109(5):e1379-e1388. doi: 10.1210/clinem/dgad610.
7
Availability, price, and affordability of antiseizure medicines in Addis Ababa, Ethiopia.
Epilepsia Open. 2023 Sep;8(3):1123-1132. doi: 10.1002/epi4.12792. Epub 2023 Jul 28.
8
Availability, Price and Affordability of Psychotropic Medicines in Addis Ababa, Ethiopia.
Risk Manag Healthc Policy. 2023 May 22;16:957-970. doi: 10.2147/RMHP.S409929. eCollection 2023.
10
A comprehensive survey of cancer medicines prices, availability and affordability in Ghana.
PLoS One. 2023 May 3;18(5):e0279817. doi: 10.1371/journal.pone.0279817. eCollection 2023.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验