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肝内胆管结石外科治疗的进展

Evolution of surgical treatment for hepatolithiasis.

作者信息

Ye Yong-Qing, Li Pei-Heng, Wu Qing, Yang Shang-Lin, Zhuang Bao-Ding, Cao Ya-Wen, Xiao Zhan-Yi, Wen Shun-Qian

机构信息

Department of Hepatobiliary Surgery, The Second People's Hospital of Foshan, Foshan 528000, Guangdong Province, China.

Department of Oncology, Foshan Nanhai District Fifth People's Hospital, Foshan 528000, Guangdong Province, China.

出版信息

World J Gastrointest Surg. 2024 Dec 27;16(12):3666-3674. doi: 10.4240/wjgs.v16.i12.3666.

DOI:10.4240/wjgs.v16.i12.3666
PMID:39734463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11650219/
Abstract

Hepatolithiasis is a common disease where stones are located in the intrahepatic bile duct. Hepatolithiasis is a disease with regional characteristics. The complication and postoperative recurrence rates of the disease are high. The intrahepatic cholangiocarcinoma and the incidence of liver cirrhosisare the main causes of death in patients with hepatolithiasis. Thus, it is difficult to treat. The majority of biliary stones are readily removed endoscopically, however complex intrahepatic or large refractory extrahepatic stones often require surgical or percutaneous interventions when standard endoscopic methods fail. At present, the main clinical treatment for hepatolithiasis is surgery, of which there are different methods depending on the patient's condition. With the continuous updates and development of medical technology, the treatment of hepatolithiasis has improved. In this paper, several mainstream surgical methods including partial hepatectomy, choledochojejunostomy, biliary tract exploration and lithotomy, percutaneous transhepatic chledochoscopic lithotripsy and liver transplantation used in the clinic are reviewed for clinicians' reference. Depending on the characteristics of each case, a suitable surgical method is chosen to obtain the best treatment effect.

摘要

肝内胆管结石是一种结石位于肝内胆管的常见疾病。肝内胆管结石是一种具有地域特征的疾病。该疾病的并发症和术后复发率较高。肝内胆管癌和肝硬化的发生率是肝内胆管结石患者的主要死因。因此,其治疗难度较大。大多数胆管结石可通过内镜轻松取出,然而,当标准内镜方法失败时,复杂的肝内结石或难治性肝外大结石通常需要手术或经皮介入治疗。目前,肝内胆管结石的主要临床治疗方法是手术,其中根据患者病情有不同的手术方式。随着医学技术的不断更新和发展,肝内胆管结石的治疗已有改善。本文对临床上使用的几种主流手术方法进行综述,包括肝部分切除术、胆总管空肠吻合术、胆道探查取石术、经皮经肝胆道镜碎石术和肝移植术,以供临床医生参考。根据每个病例的特点,选择合适的手术方法以获得最佳治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf7d/11650219/75320e2ada4c/WJGS-16-3666-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf7d/11650219/75320e2ada4c/WJGS-16-3666-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf7d/11650219/75320e2ada4c/WJGS-16-3666-g001.jpg

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1
Evolution of surgical treatment for hepatolithiasis.肝内胆管结石外科治疗的进展
World J Gastrointest Surg. 2024 Dec 27;16(12):3666-3674. doi: 10.4240/wjgs.v16.i12.3666.
2
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本文引用的文献

1
Three-dimensional visualization technology for guiding one-step percutaneous transhepatic cholangioscopic lithotripsy for the treatment of complex hepatolithiasis.一步法经皮经肝胆道镜碎石取石术治疗复杂肝胆管结石的三维可视化技术。
World J Gastroenterol. 2024 Jul 28;30(28):3393-3402. doi: 10.3748/wjg.v30.i28.3393.
2
Precision Liver Resection: Three-Dimensional Reconstruction Combined with Fluorescence Laparoscopic Imaging.精准肝切除:三维重建联合荧光腹腔镜成像。
Surg Innov. 2021 Feb;28(1):71-78. doi: 10.1177/1553350620954581. Epub 2020 Sep 2.
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Management of Hepatolithiasis: Review of the Literature.
肝内胆管结石的治疗:文献综述
Curr Gastroenterol Rep. 2020 May 7;22(6):30. doi: 10.1007/s11894-020-00765-3.
4
Comparative safety and effectiveness of ultrasound-guided radiofrequency ablation combined with preoperative three-dimensional reconstruction versus surgical resection for solitary hepatocellular carcinoma of 3-5 cm.超声引导下射频消融联合术前三维重建与手术切除治疗3-5cm孤立性肝细胞癌的安全性及有效性比较
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Lancet. 2019 Sep 7;394(10201):869-881. doi: 10.1016/S0140-6736(19)31894-X.
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Severe hypercalcemia preceding a diagnosis of Pneumocystis jirovecii pneumonia in a liver transplant recipient.肝移植受者在诊断肺孢子菌肺炎之前发生严重高钙血症。
BMC Infect Dis. 2019 Aug 22;19(1):739. doi: 10.1186/s12879-019-4370-z.
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Laparoscopic approach for choledochojejunostomy.腹腔镜胆总管空肠吻合术
Hepatobiliary Pancreat Dis Int. 2019 Jun;18(3):285-288. doi: 10.1016/j.hbpd.2019.04.004. Epub 2019 Apr 17.
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What Is Hot and New in Basic Science in Liver Transplantation in 2018? Report of the Basic Science Committee of the International Liver Transplantation Society.
Transplantation. 2019 Apr;103(4):654-659. doi: 10.1097/TP.0000000000002617.
9
The effect of liver transplantation on patient-centred outcomes: a propensity-score matched analysis.肝移植对以患者为中心的结局的影响:倾向评分匹配分析。
Transpl Int. 2019 Aug;32(8):808-819. doi: 10.1111/tri.13416. Epub 2019 Mar 20.
10
Plant-Based Diet, Cholesterol, and Risk of Gallstone Disease: A Prospective Study.植物性饮食、胆固醇与胆囊疾病风险:一项前瞻性研究。
Nutrients. 2019 Feb 4;11(2):335. doi: 10.3390/nu11020335.