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骨软骨化生型气管支气管病作为慢性咳嗽的罕见病因

Tracheobronchopathia osteochondroplastica as an unusual cause of chronic cough.

作者信息

Saxena Puneet, Singh Sarvinder, Verma R N, Sharma Neeraj, Kumar Kunal, Singh Vikram

机构信息

Senior Advisor (Respiratory Medicine), Army Hospital (R&R), Delhi Cantt, India.

Consultant (Medicine & Respiratory Medicine), Army Hospital (R&R), Delhi Cantt, India.

出版信息

Med J Armed Forces India. 2024 Dec;80(Suppl 1):S260-S263. doi: 10.1016/j.mjafi.2023.01.001. Epub 2023 Mar 9.

Abstract

A cough that persists for more than 8 weeks is defined as a chronic cough. In routine practice, asthma, gastroesophageal reflux disease, and postnasal drip are the most common causes of chronic cough. A 58-year-old non-smoking male patient with no known comorbidities presented with a 3-month history of non-productive cough. Clinically, the respiratory system examination was normal, and radiological evaluation showed tracheal nodularity on computed tomography scan. He was then subjected to bronchoscopy, which showed multiple white-colored nodules involving the anterolateral wall of the tracheobronchial tree with the sparing of the posterior membranous wall. The bronchoscopic picture was the characteristic of Tracheobronchopathia osteochondroplastica (TBOP) and was later confirmed on histopathological examination of the nodules. TBOP presenting as chronic cough is very rare. It is a rare benign disease of the tracheobronchial tree and does not warrant any active intervention in the majority of patients.

摘要

持续超过8周的咳嗽被定义为慢性咳嗽。在常规临床实践中,哮喘、胃食管反流病和鼻后滴漏是慢性咳嗽最常见的病因。一名58岁无吸烟史且无已知合并症的男性患者出现了3个月的干咳病史。临床上,呼吸系统检查正常,影像学评估显示计算机断层扫描上气管有结节。随后他接受了支气管镜检查,结果显示气管支气管树的前外侧壁有多个白色结节,而后壁膜部未受累。支气管镜检查结果具有骨软骨成形性气管支气管病(TBOP)的特征,随后结节的组织病理学检查证实了这一诊断。以慢性咳嗽为表现的TBOP非常罕见。它是气管支气管树的一种罕见良性疾病,在大多数患者中无需任何积极干预。

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Tracheobronchopathia osteochondroplastica as an unusual cause of chronic cough.骨软骨化生型气管支气管病作为慢性咳嗽的罕见病因
Med J Armed Forces India. 2024 Dec;80(Suppl 1):S260-S263. doi: 10.1016/j.mjafi.2023.01.001. Epub 2023 Mar 9.

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Tracheobronchopathia osteochondroplastica: a study of 41 patients.骨化性气管支气管病:41例患者的研究
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