Branco Sofia, Nogueira Machado Sara, Azevedo Inês, Carvalho Isabel, Silva Sónia
Pediatrics, Unidade Local de Saúde Póvoa de Varzim/Vila do Conde, Póvoa de Varzim, PRT.
Pediatrics, Unidade Local de Saúde São João, Porto, PRT.
Cureus. 2024 Nov 28;16(11):e74678. doi: 10.7759/cureus.74678. eCollection 2024 Nov.
Tuberculosis (TB) continues to pose a significant health challenge globally and in Portugal. Diagnostic challenges persist, especially in infants, where TB often presents with atypical symptoms. A previously healthy three-month-old male infant from Vila Nova de Famalicão, Portugal, was admitted with cough, rhinorrhea, respiratory distress, and high-grade fever. After chest radiography and blood tests, he was treated with ampicillin for community-acquired pneumonia (CAP). Initial antibiotic therapy proved ineffective, and subsequent imaging showed necrotizing pneumonia. Thoracic computed tomography and bronchoscopy revealed a significant consolidation with cavitation and lymphatic involvement, as well as extrinsic compression of the right main bronchus. Gastric aspirates (GA) and bronchoalveolar lavage (BAL) washings grew . Treatment eventually with antituberculosis drugs and prednisolone resulted in clinical and radiological improvement. Subsequent immunological evaluations were normal.
结核病（TB）在全球和葡萄牙仍然是一项重大的健康挑战。诊断难题依然存在，尤其是在婴儿中，结核病常常表现出非典型症状。一名来自葡萄牙法马利康新镇的三个月大健康男婴因咳嗽、流涕、呼吸窘迫和高热入院。经胸部X光检查和血液检测后，他因社区获得性肺炎（CAP）接受了氨苄青霉素治疗。最初的抗生素治疗无效，随后的影像学检查显示为坏死性肺炎。胸部计算机断层扫描和支气管镜检查显示有明显的实变并伴有空洞形成及淋巴结受累，以及右主支气管的外部压迫。胃抽吸物（GA）和支气管肺泡灌洗（BAL）洗液培养出……最终使用抗结核药物和泼尼松龙治疗后，临床和影像学表现均有改善。随后的免疫学评估结果正常。
