Oral Sukru, Sahin Ali, Durmus Ninetullah A, Ulutabanca Halil, Koç Kemal
Neurosurgery, Erciyes University Faculty of Medicine, Kayseri, TUR.
Cureus. 2024 Nov 27;16(11):e74632. doi: 10.7759/cureus.74632. eCollection 2024 Nov.
Intramedullary schwannomas are a type of benign spinal cord tumor that originates from the Schwann cells of the nerve sheath. They are relatively rare and typically occur within the spinal cord itself, rather than in the surrounding tissue. Treatment options for cervical intramedullary schwannomas include surgical removal of the tumor, radiation therapy, and observation. Surgery is often considered the first-line treatment, as complete removal of the tumor can provide the best outcome for patients. However, the choice of treatment will depend on various factors such as the size and location of the tumor. In this study, a case of intramedullary schwannoma located in the cervical region is presented and the literature is reviewed. The literature review searched through some databases, including PubMed, Elsevier, and Ovid Medline, and found a total of 83 cases of intramedullary cervical schwannomas reported in 70 articles since 1932. Forty-nine of the cases were male, 34 of them were female and the mean age was 38.9 years. The cases associated with neurofibromatosis were not included in this study. Astrocytoma, ependymoma, and schwannoma are all tumors that can occur within the spinal cord, but they have different origins, different characteristics, and different growth patterns. Astrocytomas and ependymomas are more commonly found in intramedullary locations within the spinal cord, compared to schwannomas. In summary, when intramedullary tumors are suspected, it's important to consider schwannomas as a differential diagnosis.
髓内神经鞘瘤是一种起源于神经鞘雪旺细胞的良性脊髓肿瘤。它们相对罕见,通常发生在脊髓本身,而非周围组织。颈椎髓内神经鞘瘤的治疗选择包括手术切除肿瘤、放射治疗和观察。手术通常被视为一线治疗方法,因为完全切除肿瘤可为患者提供最佳预后。然而,治疗方法的选择将取决于多种因素,如肿瘤的大小和位置。在本研究中,报告了一例位于颈椎区域的髓内神经鞘瘤病例并对文献进行了综述。文献综述检索了包括PubMed、爱思唯尔和Ovid Medline在内的一些数据库,自1932年以来在70篇文章中总共发现了83例颈椎髓内神经鞘瘤病例报告。其中49例为男性,34例为女性,平均年龄为38.9岁。本研究未纳入与神经纤维瘤病相关的病例。星形细胞瘤、室管膜瘤和神经鞘瘤都是可发生在脊髓内的肿瘤,但它们有不同的起源、不同的特征和不同的生长模式。与神经鞘瘤相比,星形细胞瘤和室管膜瘤更常见于脊髓内的髓内位置。总之,当怀疑有髓内肿瘤时,将神经鞘瘤作为鉴别诊断很重要。