Ahmed Gasim, Sheikh Usman, Dawson Timothy, Sonwalker Hemant
Radiology, The Christie Hospital NHS Foundation Trust, Manchester, GBR.
Radiology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, GBR.
Cureus. 2021 Feb 8;13(2):e13228. doi: 10.7759/cureus.13228.
Spinal schwannomas are benign WHO grade I nerve sheath tumors that account for nearly 30% of all spinal neoplasm. Typically, these lesions are intradural extramedullary in location and are composed entirely of well-differentiated eosinophilic Schwann cells. Intramedullary schwannomas, however, are extremely rare due to the lack of Schwan cells in the normal spinal cord and represent 1% of all the spinal schwannoma population. The presence of such an intramedullary component makes diagnosis challenging as imaging features may resemble other intramedullary neoplastic entities. Here, we describe a case of a 56-year-old male patient who presented with an 18-month history of intermittent right-sided mid-thoracic pain secondary to multiple intradural extramedullary spinal schwannoma with intramedullary extensions. We also review the literature pertaining to the condition.
脊髓神经鞘瘤是世界卫生组织一级良性神经鞘瘤,占所有脊髓肿瘤的近30%。通常,这些病变位于硬膜内髓外,完全由分化良好的嗜酸性雪旺细胞组成。然而,由于正常脊髓中缺乏雪旺细胞,髓内神经鞘瘤极为罕见,占所有脊髓神经鞘瘤患者的1%。这种髓内成分的存在使得诊断具有挑战性,因为影像学特征可能与其他髓内肿瘤实体相似。在此,我们描述一例56岁男性患者,其因多发硬膜内髓外脊髓神经鞘瘤并伴有髓内延伸,出现了18个月间歇性右侧胸中段疼痛的病史。我们还回顾了与该疾病相关的文献。