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伴有髓内扩展的多发性硬脊膜内髓外脊髓神经鞘瘤罕见病例。

Rare Case of Multiple Intradural Extramedullary Spinal Schwannomas With Intramedullary Extension.

作者信息

Ahmed Gasim, Sheikh Usman, Dawson Timothy, Sonwalker Hemant

机构信息

Radiology, The Christie Hospital NHS Foundation Trust, Manchester, GBR.

Radiology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, GBR.

出版信息

Cureus. 2021 Feb 8;13(2):e13228. doi: 10.7759/cureus.13228.

Abstract

Spinal schwannomas are benign WHO grade I nerve sheath tumors that account for nearly 30% of all spinal neoplasm. Typically, these lesions are intradural extramedullary in location and are composed entirely of well-differentiated eosinophilic Schwann cells. Intramedullary schwannomas, however, are extremely rare due to the lack of Schwan cells in the normal spinal cord and represent 1% of all the spinal schwannoma population. The presence of such an intramedullary component makes diagnosis challenging as imaging features may resemble other intramedullary neoplastic entities. Here, we describe a case of a 56-year-old male patient who presented with an 18-month history of intermittent right-sided mid-thoracic pain secondary to multiple intradural extramedullary spinal schwannoma with intramedullary extensions. We also review the literature pertaining to the condition.

摘要

脊髓神经鞘瘤是世界卫生组织一级良性神经鞘瘤,占所有脊髓肿瘤的近30%。通常,这些病变位于硬膜内髓外,完全由分化良好的嗜酸性雪旺细胞组成。然而,由于正常脊髓中缺乏雪旺细胞,髓内神经鞘瘤极为罕见,占所有脊髓神经鞘瘤患者的1%。这种髓内成分的存在使得诊断具有挑战性,因为影像学特征可能与其他髓内肿瘤实体相似。在此,我们描述一例56岁男性患者,其因多发硬膜内髓外脊髓神经鞘瘤并伴有髓内延伸,出现了18个月间歇性右侧胸中段疼痛的病史。我们还回顾了与该疾病相关的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2baa/7946570/c1a0b0c9a420/cureus-0013-00000013228-i01.jpg

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