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埃及上下埃及地区的乙型肝炎病毒感染

Hepatitis B virus infection in upper and lower Egypt.

作者信息

Sherif M M, Abou-Aita B A, Abou-Elew M H, el-Kafrawi A O

出版信息

J Med Virol. 1985 Feb;15(2):129-35. doi: 10.1002/jmv.1890150205.

DOI:10.1002/jmv.1890150205
PMID:3973568
Abstract

The relative prevalence of hepatitis B surface antigen (HBsAg), anti-HBs, and anti-hepatitis B virus core antigen (HBc), as markers of hepatitis B virus infection, among 1,866 apparently healthy residents of two Egyptian provinces representing Upper and Lower Egypt populations was determined using solid-phase radioimmunoassay (SPRIA). The prevalence rate of HBsAg in the Egyptian population was moderately high (10.1%); it was higher in the Upper Egypt (11.7%) than the Lower Egypt (8.0%) population and more frequent in young adults--especially those of Upper Egypt--and males than females in both populations. The prevalence of anti-HBs gradually increased with age; it was higher in the Lower Egypt (51.1%) than the Upper Egypt (41.7%) population, and it was higher in females than males. A remarkably high infection rate, as shown by the prevalence of anti-HBc, was found in both populations (88.0%), with minor variations depending on age, sex, and geographic area.

摘要

采用固相放射免疫分析法(SPRIA)测定了代表埃及上埃及和下埃及人群的两个省份中1866名表面健康居民的乙肝表面抗原(HBsAg)、乙肝表面抗体(抗-HBs)和乙肝核心抗体(抗-HBc)作为乙肝病毒感染标志物的相对流行情况。埃及人群中HBsAg的流行率中等偏高(10.1%);在上埃及人群(11.7%)中高于下埃及人群(8.0%),且在两个群体中,年轻人——尤其是上埃及的年轻人——以及男性中的流行频率高于女性。抗-HBs的流行率随年龄逐渐升高;在下埃及人群(51.1%)中高于上埃及人群(41.7%),且女性高于男性。两个群体中抗-HBc的流行率均显示出极高的感染率(88.0%),因年龄、性别和地理区域的不同存在细微差异。

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