Hyams K C, McCarthy M, el-Shimy S, el-Samahy M, Mansour M M, Imam I Z
Epidemiology Division, Naval Medical Research Institute, Bethesda, MD 20814-5055.
Infection. 1990 Sep-Oct;18(5):273-6. doi: 10.1007/BF01647001.
One-hundred and four cases of acute viral hepatitis and 100 controls 13 years of age and less were entered into a study of acute hepatitis in children in Cairo, Egypt. Study subjects, who were mainly from a lower socioeconomic level, were selected from a public pediatric clinic. Acute non-A, non-B hepatitis was diagnosed in 51 (49%) patients, hepatitis A in 46 (44%), possible hepatitis B in three (3%), and EBV hepatitis in four (4%) patients. Contact with a family member with jaundice was found to be significantly associated with hepatitis A. A history of a blood transfusion, a medical injection, and knowledge of an individual outside of the household with jaundice during the prior six months were significantly associated with non-A, non-B hepatitis. A significant association was not found between the type of hepatitis and the age and gender of study subjects and the extent of household crowding. In this pediatric population living in an urban area of a developing country, non-A, non-B hepatitis was found to be a major cause of acute sporadic hepatitis.
104例急性病毒性肝炎患儿及100例13岁及以下的对照儿童被纳入埃及开罗儿童急性肝炎的研究。研究对象主要来自社会经济水平较低的群体，从一家公立儿科诊所选取。51例（49%）患者被诊断为急性非甲非乙型肝炎，46例（44%）为甲型肝炎，3例（3%）可能为乙型肝炎，4例（4%）为EB病毒肝炎。发现与黄疸家庭成员接触与甲型肝炎显著相关。输血史、医疗注射史以及在过去六个月内知晓家庭外有黄疸患者与非甲非乙型肝炎显著相关。未发现肝炎类型与研究对象的年龄、性别以及家庭拥挤程度之间存在显著关联。在这个生活在发展中国家城市地区的儿科人群中，非甲非乙型肝炎被发现是急性散发性肝炎的主要病因。
