Arif Syed Abdul, Lahkar Deepa, Gogoi Sophia Makdoh, Changkija Bendangla, Kakati Parikshit, Buragohain Lukumoni, Pathak Mamta, Das Tinku
Division of Veterinary Medicine, ICAR-Indian Veterinary Research Institute, Izatnagar (IVRI), Bareilly, Uttar Pradesh, India.
Department of Veterinary Medicine, College of Veterinary Science, Assam, India.
Iran J Parasitol. 2024 Oct-Dec;19(4):502-508. doi: 10.18502/ijpa.v19i4.17173.
A 2-year-old female Assam Hill goat was presented with a clinical history of anorexia, fever, mild anemia, rough body coat, dehydration, tachycardia, dyspnea and swelling of palpable lymph nodes. Hematology revealed low hemoglobin, packed cell volume, red blood cell and thrombocyte count. Biochemical analysis showed increased serum concentration of alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine and urea in comparison to the normal reference range. Microscopic examination showed intra-erythrocytic forms of Theileria species. Molecular and phylogenetic analysis of partial 18S rRNA gene sequence confirmed Theileria luwenshuni infection. The goat was treated with buparvaquone and oxytetracycline and recovered uneventfully. A three-month follow-up showed no recurrence. This study reveals the presence of T. luwenshuni in Assam, India and it should be considered in differential diagnosis and as one of the important pathogens of clinically sick goats. The present case report provides a rational approach to diagnosis and treatment for a goat infected with pathogenic T. luwenshuni in Assam, India. To our knowledge, the present communication describes about the first successful therapeutic management of pathogenic T. luwenshuni infection in a goat supported with molecular evidence from Assam, a north-eastern state of India.
一只2岁的阿萨姆邦山地雌性山羊，有厌食、发热、轻度贫血、被毛粗糙、脱水、心动过速、呼吸困难以及可触及淋巴结肿大的临床病史。血液学检查显示血红蛋白、红细胞压积、红细胞和血小板计数偏低。生化分析表明，与正常参考范围相比，血清丙氨酸转氨酶（ALT）、天冬氨酸转氨酶（AST）、肌酐和尿素浓度升高。显微镜检查发现红细胞内有泰勒虫属的形态。对部分18S rRNA基因序列进行分子和系统发育分析，证实感染了吕氏泰勒虫。这只山羊用丁萘脒和土霉素进行治疗，康复顺利。三个月的随访显示没有复发。本研究揭示了印度阿萨姆邦存在吕氏泰勒虫，在鉴别诊断中应予以考虑，它是临床患病山羊的重要病原体之一。本病例报告为印度阿萨姆邦感染致病性吕氏泰勒虫的山羊提供了合理的诊断和治疗方法。据我们所知，本通讯首次描述了在印度东北部阿萨姆邦一只山羊身上成功治疗致病性吕氏泰勒虫感染的案例，并提供了分子证据。
