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Cartilage. 2023 Dec;14(4):400-406. doi: 10.1177/19476035231178374. Epub 2023 Jul 3.
2
Prognostic factors for the management of chondral defects of the knee and ankle joint: a systematic review.膝关节和踝关节软骨缺损的处理的预后因素:系统评价。
Eur J Trauma Emerg Surg. 2023 Apr;49(2):723-745. doi: 10.1007/s00068-022-02155-y. Epub 2022 Nov 7.
3
Algorithm for Treatment of Focal Cartilage Defects of the Knee: Classic and New Procedures.膝关节局限性软骨缺损的治疗方法:经典与新术式。
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Arthroscopy. 2019 Jun;35(6):1860-1877. doi: 10.1016/j.arthro.2018.11.073. Epub 2019 Mar 11.
5
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Arthrosc Tech. 2018 Mar 26;7(4):e391-e396. doi: 10.1016/j.eats.2017.10.011. eCollection 2018 Apr.
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A new point of view for mosaicplasty in the treatment of focal cartilage defects of knee joint: honeycomb pattern.膝关节局灶性软骨缺损治疗中镶嵌植骨术的新观点:蜂窝状模式
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果冻镶嵌植骨术的功能预后

Functional Outcomes of Nuts-in-Jelly Mosaicplasty.

作者信息

Sahanand Santosh, Chellamuthu Girinivasan, V Rajan David

机构信息

Ortho One Orthopaedic Specialty Centre, Coimbatore, India.

Karpagam Academy of Higher Education, Coimbatore, India.

出版信息

Indian J Orthop. 2024 Nov 30;59(1):101-107. doi: 10.1007/s43465-024-01296-z. eCollection 2025 Jan.

DOI:10.1007/s43465-024-01296-z
PMID:39735868
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11680537/
Abstract

INTRODUCTION

Interspace defects after osteochondral autograft transfer (OATS) are filled only with fibrocartilage. Attempts have been made to address these issues in OATS with procedures like mega OATS and Hexagonal Osteochondral Graft System. We have described the functional outcomes of a hybrid technique combining a regeneration and a restoration modality to address the interspace defect in OATS.

METHODS

Consecutive cases of full-thickness focal chondral defects of the knee were treated using the nuts-in-jelly mosaicplasty technique. Patients with less than 1 cm lesions, ligament insufficiency, and alignment abnormalities were excluded. Bone marrow aspirate concentrate (BMAC) with fibrin glue has been used to fill the defect remaining after the osteochondral cylinders are transferred, resulting in a configuration like nuts dispersed in a jelly.

RESULTS

We had a total of 12 cases-4 cases of osteochondritis dessicans (OCD) and 8 cases of traumatic chondral defects. The mean age of the patients was 32 years (range 19 - 44 years). 4 were female patients. The available cartilage was fixed in all the OCD cases. The remaining defect was filled with one or two osteochondral cylinders and the BMAC-fibrin glue or only with BMAC-fibrin glue. In traumatic defect cases, the space remaining after the OATS cylinder transfer was filled with BMAC-fibrin glue. The mean follow-up period was 3 years (range 2 - 5 years). All cases had good to excellent Tegner-Lysholm scores with a mean score of 92 (range 85 - 96).

CONCLUSION

Nuts in jelly mosaicplasty may address the issue of fibrous cartilage formation after OATS in the interspace. Further prospective comparative studies are necessary to validate the findings of this study.

摘要

引言

自体骨软骨移植(OATS)术后的间隙缺损仅由纤维软骨填充。人们已尝试通过诸如大型OATS和六角形骨软骨移植系统等手术来解决OATS中的这些问题。我们描述了一种结合再生和修复方式以解决OATS中间隙缺损的混合技术的功能结果。

方法

采用“坚果在果冻”镶嵌成形术技术治疗膝关节全层局灶性软骨缺损的连续病例。排除病变小于1厘米、韧带功能不全和对线异常的患者。使用含纤维蛋白胶的骨髓抽吸浓缩物(BMAC)填充骨软骨柱转移后剩余的缺损,形成类似坚果分散在果冻中的结构。

结果

我们共纳入12例患者,其中4例为剥脱性骨软骨炎(OCD),8例为创伤性软骨缺损。患者的平均年龄为32岁(范围19 - 44岁)。4例为女性患者。所有OCD病例中可用的软骨均得以固定。剩余缺损用一或两个骨软骨柱和BMAC - 纤维蛋白胶填充,或仅用BMAC - 纤维蛋白胶填充。在创伤性缺损病例中,OATS柱转移后剩余的间隙用BMAC - 纤维蛋白胶填充。平均随访期为3年(范围2 - 5年)。所有病例的Tegner - Lysholm评分均为良好至优秀,平均评分为92分(范围85 - 96分)。

结论

“坚果在果冻”镶嵌成形术可能解决OATS术后间隙中纤维软骨形成的问题。需要进一步的前瞻性对照研究来验证本研究的结果。