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在一组异质性患者中,骨髓抽吸浓缩物联合髋关节镜检查可能会改善患者报告的结局:一项系统评价。

Bone Marrow Aspirate Concentrate With Hip Arthroscopy in a Heterogenous Group of Patients May Result in Improved Patient-Reported Outcomes: A Systematic Review.

作者信息

Lee Michael S, Pettinelli Nicholas J, Gagné Jack, Zhu Justin, Norman Mackenzie, Atadja Louise, Mahatme Ronak J, Fong Scott, Moran Jay, Gillinov Stephen M, Islam Wasif, Park Nancy, Jimenez Andrew E

机构信息

Medical College of Wisconsin, Milwaukee, USA.

Kansas City University College of Osteopathic Medicine, MO, USA.

出版信息

HSS J. 2025 Jul 3:15563316251349543. doi: 10.1177/15563316251349543.

Abstract

INTRODUCTION

There is little literature reporting on the efficacy of bone marrow aspirate concentrate (BMAC) in conjunction with hip arthroscopy.

PURPOSE

We sought to systematically review the literature on BMAC use following hip arthroscopy, in particular, whether its use results in improved patient-reported outcome measures (PROMs).

METHODS

The Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines were followed when querying PubMed, Cochrane Central Register of Controlled Trials, and Scopus in January 2023. Articles were included if they reported on pre- and postoperative outcomes for patients undergoing hip arthroscopy with concomitant BMAC and were written in English.

RESULTS

Five articles were included in the review. A total of 252 hips undergoing BMAC and hip arthroscopy performed between 2010 and 2020 were evaluated. The average age of patients in the studies ranged between 32.8 and 48.5 years. All studies reported improved postoperative PROM scores compared to preoperative outcome scores after BMAC and hip arthroscopy. Two studies reported survivorship of 100% and 85.7%. All 5 studies conducted a subanalysis between BMAC and hip arthroscopy and a control group. Three studies reported superior outcomes in the BMAC and hip arthroscopy group, while another study reported findings that trended toward favoring the BMAC and hip arthroscopy group but that did not reach statistical significance.

CONCLUSION

BMAC may improve outcomes in patients undergoing hip arthroscopy. However, due to the small sample size and lack of standardized control groups, the results of this systematic review are inconclusive.

摘要

引言

关于骨髓抽吸浓缩物(BMAC)联合髋关节镜检查疗效的文献报道较少。

目的

我们旨在系统回顾有关髋关节镜检查后使用BMAC的文献,特别是其使用是否能改善患者报告的结局指标(PROMs)。

方法

2023年1月在查询PubMed、Cochrane对照试验中心注册库和Scopus时遵循系统评价和Meta分析的首选报告项目指南。如果文章报道了接受髋关节镜检查并同时使用BMAC的患者的术前和术后结局,且为英文撰写,则纳入研究。

结果

该综述纳入了5篇文章。共评估了2010年至2020年间进行BMAC和髋关节镜检查的252例髋关节。研究中患者的平均年龄在32.8岁至48.5岁之间。所有研究均报告,与BMAC和髋关节镜检查术前结局评分相比,术后PROM评分有所改善。两项研究报告的生存率分别为100%和85.7%。所有5项研究都在BMAC和髋关节镜检查组与对照组之间进行了亚分析。三项研究报告BMAC和髋关节镜检查组的结局更好,而另一项研究报告的结果虽倾向于支持BMAC和髋关节镜检查组,但未达到统计学意义。

结论

BMAC可能改善接受髋关节镜检查患者的结局。然而,由于样本量小且缺乏标准化对照组,本系统评价的结果尚无定论。

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