Wojtulewski Adam, Sikora Aleksandra, Dineen Sean, Raoof Mustafa, Karolak Aleksandra
Department of Machine Learning, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa FL 33612, United States.
Department of Computer and Information Science and Engineering, University of Florida, 432 Newell Dr, Gainesville, FL 32611, United States.
Brief Funct Genomics. 2025 Jan 15;24. doi: 10.1093/bfgp/elae049.
The primary objective of this study is to investigate various applications of artificial intelligence (AI) and statistical methodologies for analyzing and managing peritoneal metastases (PM) caused by gastrointestinal cancers.
Relevant keywords and search criteria were comprehensively researched on PubMed and Google Scholar to identify articles and reviews related to the topic. The AI approaches considered were conventional machine learning (ML) and deep learning (DL) models, and the relevant statistical approaches included biostatistics and logistic models.
The systematic literature review yielded nearly 30 articles meeting the predefined criteria. Analyses of these studies showed that AI methodologies consistently outperformed traditional statistical approaches. In the AI approaches, DL consistently produced the most precise results, while classical ML demonstrated varied performance but maintained high predictive accuracy. The sample size was the recurring factor that increased the accuracy of the predictions for models of the same type.
AI and statistical approaches can detect PM developing among patients with gastrointestinal cancers. Therefore, if clinicians integrated these approaches into diagnostics and prognostics, they could better analyze and manage PM, enhancing clinical decision-making and patients' outcomes. Collaboration across multiple institutions would also help in standardizing methods for data collection and allowing consistent results.
本研究的主要目的是探讨人工智能(AI)和统计方法在分析和管理胃肠道癌所致腹膜转移(PM)中的各种应用。
在PubMed和谷歌学术上全面检索相关关键词和检索标准,以确定与该主题相关的文章和综述。所考虑的人工智能方法包括传统机器学习(ML)和深度学习(DL)模型,相关统计方法包括生物统计学和逻辑模型。
系统文献综述得出近30篇符合预定义标准的文章。对这些研究的分析表明,人工智能方法始终优于传统统计方法。在人工智能方法中,深度学习始终产生最精确的结果,而经典机器学习表现各异但保持较高的预测准确性。样本量是提高同一类型模型预测准确性的反复出现的因素。
人工智能和统计方法可以检测胃肠道癌患者中发生的腹膜转移。因此,如果临床医生将这些方法整合到诊断和预后中,他们可以更好地分析和管理腹膜转移,加强临床决策和改善患者预后。多机构合作也将有助于规范数据收集方法并获得一致的结果。