Alkhormani Areej Abed, Alghamdi Reema Abdullah, Damdam Yara Abdulaziz, Almaghrabi Maria Eissa, Alamri Faisal F, Khan Muhammad Anwar, Hakami Alqassem Y
College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Basic Sciences Department, College of Science and Health Professions, King Saud bin Abdulaziz University for Health Sciences, Jeddah, 22384, Saudi Arabia.
BMC Public Health. 2024 Dec 30;24(1):3613. doi: 10.1186/s12889-024-20925-8.
Post-COVID-19 syndrome refers to a variety of symptoms that affect different organs in the body and can persist 28 days following exposure to COVID-19. Previous studies have shown that COVID-19 affects not only elderly individuals but also young adults. However, the influence of post-COVID-19 syndrome on young adults has not been studied sufficiently. Therefore, the aim of this study was to determine the prevalence and characteristics of post-COVID-19 manifestations in young adults.
An analytical cross-sectional online questionnaire was distributed from July 2022 to July 2023 to health sciences students in Saudi Arabia. The study used a non-probability convenience sampling technique, and the sample size was calculated to be 464. The survey included questions about the participants' demographics, health records, COVID-19 results, duration of infection, and previous and current COVID-19 symptoms. Illness severity and management were evaluated using the COVID Experiences (COVEX) Symptoms and Diagnoses module, and Patient Health Questionnaire (PHQ-9) was used to assess depression.
According to the inclusion criteria, 428 participants were divided into three groups: those who fully recovered within 14 days of the acute phase (76.4%), those with prolonged symptoms that resolved within 28 days (16.8%), and those with persistent symptoms for more than 28 days (6.8%). The symptom development frequency during the acute phase significantly differed among the three groups: headache (p = 0.038), loss of smell and taste (p = < 0.001), and fatigue (p = 0.009). The symptoms that significantly differed between the prolonged group and persistent group during the post-COVID-19 syndrome phase were loss of smell and taste (p = < 0.001) and shortness of breath (p = < 0.001). The study results revealed that females are susceptible to long-COVID-19. This study revealed that the overall severity of post-COVID-19 symptoms was mild in this age group. The PHQ-9 score when comparing the three groups showed a significant association with depression (p = 0.035).
The study results support the perception that not only can the geriatric population suffer from post-COVID-19 syndrome but also that young adults are prone to persistent symptoms such as loss of smell and taste, which may affect their mental health status.
新冠后综合征指的是影响身体不同器官的多种症状,这些症状在接触新冠病毒后28天仍可能持续存在。此前的研究表明,新冠病毒不仅会影响老年人,也会影响年轻人。然而,新冠后综合征对年轻人的影响尚未得到充分研究。因此,本研究的目的是确定年轻人中新冠后表现的患病率和特征。
2022年7月至2023年7月,向沙特阿拉伯的健康科学专业学生发放了一份分析性横断面在线问卷。该研究采用非概率便利抽样技术,计算得出样本量为464。调查内容包括参与者的人口统计学信息、健康记录、新冠病毒检测结果、感染持续时间以及之前和当前的新冠症状。使用新冠经历(COVEX)症状与诊断模块评估疾病严重程度和治疗情况,并使用患者健康问卷(PHQ - 9)评估抑郁情况。
根据纳入标准,428名参与者被分为三组:急性期14天内完全康复的(76.4%)、症状持续28天内缓解的(16.8%)以及症状持续超过28天的(6.8%)。三组在急性期症状出现频率上存在显著差异:头痛(p = 0.038)、嗅觉和味觉丧失(p < 0.001)以及疲劳(p = 0.009)。在新冠后综合征阶段,症状持续组和症状迁延组之间存在显著差异的症状为嗅觉和味觉丧失(p < 0.001)以及呼吸急促(p < 0.001)。研究结果显示女性易患新冠长期症状。本研究表明该年龄组新冠后症状的总体严重程度较轻。比较三组时,PHQ - 9评分与抑郁存在显著关联(p = 0.035)。
研究结果支持了这样一种观点,即不仅老年人群会患新冠后综合征,年轻人也容易出现嗅觉和味觉丧失等持续症状,这可能会影响他们的心理健康状况。