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一种基于社会网络分析的新型方法,用于分析伊朗参与抗癌药物可及性的复杂行为者网络。

A novel social-network-analysis-based approach for analyzing complex network of actors involved in accessibility of anti-cancer medications in Iran.

作者信息

Lankarani Kamran Bagheri, Zarei Leila, Alinezhad Esmaeil, Sadeghdoost Adel

机构信息

Gastroenterology and Hepatology, Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.

PharmacoEconomics and Pharmaceutical Management, Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Health Res Policy Syst. 2024 Dec 30;22(1):178. doi: 10.1186/s12961-024-01274-9.

Abstract

BACKGROUND

The access to anti-cancer medications is influenced by policies formed via the convergence of various stakeholders. The aim of this study is to identify and analyse the stakeholders involved in formulating and implementing policies related to the accessibility of anti-cancer medications in Iran and their interactions that are relevant to the outcomes of these policies for the first time.

METHODS

To achieve the objectives, a novel multistage social network analysis (SNA)-based approach that includes three phases is proposed. First, the actors were identified by a team consisting of multidisciplinary knowledgeable experts through 15 comprehensive interviews. Then, the influence relationships of these actors were comprehensively analysed through in-depth interviews with nine key informants involved in pharmaceutical policies through a structured questionnaire. Finally, a novel network of actors was determined accordingly, and a SNA-based approach proposed to reveal the intrinsic roles and various aspects of the importance of the network's actors.

RESULTS

The study identified a total of 45 actors, which were then classified into 4 categories on the basis of their public or private nature and their foreign or domestic origin. This established network helped in creating a comprehensive view of the main actors, and can help policymakers to solve the problems related to access to anti-cancer medications more effectively and prevent the creation of these problems in the future. In this way, the network identified specific actors that can benefit from increased attention and dialogue. The computational results revealed that the Iran Food and Drug Administration (IFDA), Pharmaceutical Importer Companies (PharIc) and Pharmaceutical Manufacturing Companies (PharMC) were highly important actors in terms of their connectivity to other actors. Additionally, law enforcement agencies (LEA) have shown limited effectiveness within this network.

CONCLUSIONS

This study highlights the importance of complex relationships among various actors and proposes a novel SNA-based approach to analyse them. Regarding the main steps of the proposed approach and the findings, it is imperative for pharmaceutical policy plans to involve a diverse group of experts from the beginning, prioritizing the preferences of stakeholders, and providing a patient-centred approach to prevent the worsening of resource shortages.

摘要

背景

抗癌药物的可及性受到由不同利益相关者共同形成的政策的影响。本研究的目的是首次识别和分析参与制定和实施伊朗抗癌药物可及性相关政策的利益相关者及其与这些政策结果相关的互动。

方法

为实现这些目标,提出了一种基于新颖的多阶段社会网络分析(SNA)的方法,该方法包括三个阶段。首先,由一个由多学科知识渊博的专家组成的团队通过15次全面访谈确定行动者。然后,通过对9名参与制药政策的关键信息提供者进行结构化问卷调查,深入访谈全面分析这些行动者的影响关系。最后,据此确定了一个新颖的行动者网络,并提出了一种基于SNA的方法来揭示网络行动者的内在角色和重要性的各个方面。

结果

该研究共识别出45个行动者,然后根据其公共或私人性质以及外国或国内来源将其分为4类。这个建立的网络有助于全面了解主要行动者,并可帮助政策制定者更有效地解决与抗癌药物可及性相关的问题,并防止未来出现这些问题。通过这种方式,该网络识别出了可以从更多关注和对话中受益的特定行动者。计算结果表明,伊朗食品药品管理局(IFDA)、药品进口公司(PharIc)和药品制造公司(PharMC)在与其他行动者的联系方面是非常重要的行动者。此外,执法机构(LEA)在这个网络中显示出有限的效力。

结论

本研究强调了不同行动者之间复杂关系的重要性,并提出了一种基于SNA的新颖方法来分析它们。关于所提出方法的主要步骤和研究结果,制药政策计划必须从一开始就纳入不同的专家群体,优先考虑利益相关者的偏好,并提供以患者为中心的方法,以防止资源短缺情况恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79ba/11684281/d2718d52a729/12961_2024_1274_Fig1_HTML.jpg

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