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马什哈德15至35岁人群中的血清阳性率。 (原文中“Seroprevalence of ”后面似乎缺少具体内容)

Seroprevalence of in a population of 15 to 35 years old in Mashhad.

作者信息

Khoshakhlagh Mahdieh, Tarahomi Mohammadreza, Asgharian Fatemeh, Kamali Arghavan, Abadi Safoora Sa'd, Jafarpour Kimia, Abolbashari Samaneh, Meshkat Mojtaba, Gholoobi Aida

机构信息

Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Iran J Microbiol. 2024 Dec;16(6):773-779. doi: 10.18502/ijm.v16i6.17255.

Abstract

BACKGROUND AND OBJECTIVES

is a bacterium involved in gastrointestinal disorders with a high prevalence in Iran. We have determined the seroprevalence of in the young adult population of Mashhad city for the first time.

MATERIALS AND METHODS

We carried out a cross-sectional study on 933 individuals between the ages of 15 and 35 in Mashhad. The serum level of IgG, IgM, and IgA antibodies was determined using enzyme linked immunosorbent assay (ELISA) method.

RESULTS

The average age of the participants including 290 (31.0%) male and 643 (68.9%) female cases was 25.47 ± 5.76. IgG was seropositive in 365 (39.1%) of subjects. Occupation (p=0.002), body mass index (p=0.002), marital status (p<0.0001), and age (p<0.007) were meaningfully related to IgG seropositivity. Other factors such as sex, educational attainment, history of chronic diseases, and smoking cigarette had no significant relationship with the presence of antibodies.

CONCLUSION

The seroprevalence of IgG antibodies in Mashhad's 15 to 35 years old citizens was determined 39.1%. We suggest further studies with larger sample sizes and different age groups as the target population.

摘要

背景与目的

[某种细菌名称]是一种与胃肠道疾病相关的细菌,在伊朗患病率很高。我们首次确定了马什哈德市年轻成年人群中[该细菌名称]的血清阳性率。

材料与方法

我们对马什哈德市933名年龄在15至35岁之间的个体进行了横断面研究。采用酶联免疫吸附测定(ELISA)法测定IgG、IgM和IgA[该细菌名称]抗体的血清水平。

结果

参与者的平均年龄为25.47±5.76岁,其中包括290例(31.0%)男性和643例(68.9%)女性。365名(39.1%)受试者的[该细菌名称]IgG呈血清阳性。职业(p=0.002)、体重指数(p=0.002)、婚姻状况(p<0.0001)和年龄(p<0.007)与[该细菌名称]IgG血清阳性有显著相关性。其他因素,如性别、教育程度、慢性病病史和吸烟,与[该细菌名称]抗体的存在无显著关系。

结论

马什哈德市15至35岁公民中[该细菌名称]IgG抗体的血清阳性率为39.1%。我们建议以更大样本量和不同年龄组作为目标人群进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f52/11682552/e0c256a2092e/IJM-16-773-g001.jpg

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