伊朗西南部健康献血者中 与 ABO/rh 血型抗原的血清流行率之间的关系。
Associations between seroprevalence of and ABO/rhesus blood group antigens in healthy blood donors in southwest Iran.
机构信息
Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Microbiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
出版信息
J Int Med Res. 2021 Dec;49(12):3000605211058870. doi: 10.1177/03000605211058870.
OBJECTIVE
To investigate correlations between ABO/rhesus (Rh) blood group antigens and anti- and anti-cytotoxin-associated gene A (CagA) seropositivity in blood donors.
METHODS
A total of 311 blood donors were enrolled. ABO and Rh blood groups were determined using hemagglutination tests. Specific anti- IgG and anti-CagA IgG antibodies in sera were quantitated by enzyme-linked immunosorbent assay. Correlations between blood groups and anti- and anti-CagA seropositivity were evaluated using the Chi-square test.
RESULTS
O+ was the most frequent blood type (38%, n = 118). Anti- IgG seropositivity was observed in 240 (77.2%) blood donors, while anti-CagA IgG seropositivity was observed in 132 (42.5%) blood donors. Although seropositivity rates for both anti- and anti-CagA IgG were higher in individuals with blood type O, no statistically significant associations were observed between seropositivity and any ABO/Rh blood groups.
CONCLUSION
Individuals with blood type O may have higher rates of seropositivity.
目的
调查献血者 ABO/Rh（恒河猴）血型抗原与抗和抗细胞毒素相关基因 A（CagA）血清阳性之间的相关性。
方法
共纳入 311 名献血者。采用血凝试验检测 ABO 和 Rh 血型。通过酶联免疫吸附试验定量检测血清中特异性抗 IgG 和抗 CagA IgG 抗体。采用卡方检验评估血型与抗和抗 CagA 血清阳性之间的相关性。
结果
O+是最常见的血型（38%，n=118）。240 名（77.2%）献血者抗 IgG 血清阳性，132 名（42.5%）献血者抗 CagA IgG 血清阳性。尽管 O 型血个体的抗-和抗-CagA IgG 血清阳性率均较高，但血清阳性与任何 ABO/Rh 血型之间均无统计学显著相关性。
结论
O 型血个体的抗-血清阳性率可能更高。
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